Date published: 2026-3-17

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RNase H1 Activators

The chemical class RNase H1 Activators encompasses a range of compounds that can indirectly influence the activity of RNase H1 through their impact on cellular metabolism and nucleic acid processing. These activators do not directly interact with RNase H1 but modulate various biochemical and cellular processes that can impact RNase H1 activity. Compounds such as Magnesium Chloride and Zinc Sulfate can enhance RNase H1 activity by providing essential cofactors or by influencing the overall metabolism of nucleic acids. Magnesium, as a direct cofactor, is crucial for the catalytic function of RNase H1. Zinc, known for its role in DNA and RNA metabolism, could create conditions favorable for RNase H1 activity.

Other compounds like ATP, Niacin, and Caffeine influence the cellular energy state and overall metabolic processes, which can indirectly affect RNase H1. The availability of essential vitamins like Riboflavin, Thiamine, and Folic Acid is vital for nucleotide synthesis and repair processes, which in turn can impact RNase H1 activity. Furthermore, antioxidants such as Selenium and Alpha-Lipoic Acid, by protecting cellular components, including nucleic acids, can indirectly influence RNase H1's role in nucleic acid metabolism.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Magnesium chloride

7786-30-3sc-255260C
sc-255260B
sc-255260
sc-255260A
10 g
25 g
100 g
500 g
$28.00
$35.00
$48.00
$125.00
2
(1)

Magnesium is a cofactor required for the catalytic activity of RNase H1. Providing magnesium ions via Magnesium Chloride could enhance the enzyme's activity.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc ions are known to influence DNA and RNA metabolism. Supplementing with Zinc Sulfate might indirectly affect RNase H1 activity by modulating nucleic acid processing enzymes.

Adenosine 5′-Triphosphate, disodium salt

987-65-5sc-202040
sc-202040A
1 g
5 g
$39.00
$75.00
9
(1)

ATP is crucial for numerous cellular processes, including nucleic acid metabolism. Its presence can influence the cellular energy state and indirectly affect RNase H1 activity.

Nicotinic Acid

59-67-6sc-205768
sc-205768A
250 g
500 g
$62.00
$124.00
1
(1)

Niacin, a form of Vitamin B3, is essential for the synthesis of NAD+, a coenzyme in cellular metabolism that can indirectly influence RNase H1 activity by affecting overall cellular metabolism.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine influences cellular metabolism and can impact DNA/RNA synthesis processes, potentially affecting RNase H1 activity indirectly.

Vitamin B12

68-19-9sc-296695
sc-296695A
sc-296695B
sc-296695C
sc-296695D
sc-296695E
100 mg
1 g
5 g
25 g
100 g
1 kg
$60.00
$90.00
$325.00
$1155.00
$3851.00
$10056.00
2
(1)

Vitamin B12 is crucial for DNA synthesis and repair. Its role in nucleic acid metabolism could indirectly impact RNase H1 activity.

Folic Acid

59-30-3sc-204758
10 g
$73.00
2
(1)

Folic Acid is involved in nucleotide synthesis. Its availability can influence DNA and RNA metabolism, potentially impacting RNase H1 activity.

Riboflavin

83-88-5sc-205906
sc-205906A
sc-205906B
25 g
100 g
1 kg
$41.00
$112.00
$525.00
3
(1)

Riboflavin, or Vitamin B2, is a precursor for FAD, a coenzyme in several metabolic reactions that can indirectly influence RNase H1 activity.

Vitamin B1

59-43-8sc-338735
5 g
$611.00
(0)

Thiamine, or Vitamin B1, is involved in carbohydrate metabolism, which can indirectly influence nucleic acid metabolism and RNase H1 activity.

Pyridoxine Hydrochloride

58-56-0sc-219674
10 mg
$42.00
(0)

Pyridoxine is involved in amino acid metabolism, which can indirectly impact nucleic acid synthesis and processing, potentially affecting RNase H1 activity.