RNA pol α Inhibitors
The chemical class termed RNA polymerase α inhibitors encompasses a diverse group of compounds intricately designed to modulate the activity of RNA polymerase α, an enzyme crucially involved in the transcription of genetic information from DNA to RNA. These inhibitors are meticulously crafted through an interplay of molecular insights and mechanistic understanding, often utilizing advanced techniques such as computational modeling, high-throughput screening, and chemical synthesis. The primary objective is to engineer compounds with precision to selectively interact with RNA polymerase α, potentially influencing its role in transcriptional processes.
By targeting RNA polymerase α, these inhibitors offer essential tools for exploring the intricate mechanisms that govern gene expression, RNA synthesis, and cellular regulation. The exploration of RNA polymerase α inhibitors contributes to a deeper understanding of the finely tuned interactions within the transcriptional machinery, shedding light on the nuanced dynamics that orchestrate genetic transcription and its impact on cellular functions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
This natural toxin is found in certain mushroom species and is known to inhibit RNA Pol II, which is structurally related to RNA Pol α. | ||||||
Foscarnet sodium | 63585-09-1 | sc-205330 sc-205330A | 1 g 5 g | $186.00 $663.00 | ||
This antiviral drug has been explored for its interactions with RNA Pol α and its potential role in inhibiting viral RNA synthesis. | ||||||
Phleomycin | 11006-33-0 | sc-204845 sc-204845A | 5 mg 25 mg | $191.00 $485.00 | ||
This antibiotic has been studied for its interactions with RNA Pol α and its potential role in modulating transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D, this antibiotic has been explored for its potential inhibitory effects on RNA Pol α and its impact on gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
This antibiotic is known to inhibit bacterial RNA polymerases and may also have effects on RNA Pol α. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $240.00 | ||
An experimental compound, CX-5461 has been studied for its potential inhibitory effects on RNA Pol I, but it may also impact RNA Pol α. | ||||||
Bleomycin Sulfate | 9041-93-4 | sc-200134 sc-200134A sc-200134B sc-200134C | 10 mg 50 mg 100 mg 500 mg | $206.00 $612.00 $1020.00 $2856.00 | 38 | |
This antibiotic has been explored for its interactions with RNA Pol α and its potential role in modulating gene expression. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $240.00 | 9 | |
An experimental compound, bryostatin 1 has been investigated for its potential effects on RNA Pol II, which may have implications for RNA Pol α. | ||||||
Actinomycin V | 18865-48-0 | sc-507379 | 1 mg | $450.00 | ||
This antibiotic has been studied for its potential interactions with RNA Pol α and its impact on transcription processes. | ||||||