RN-tre activators are a collection of chemical compounds that enhance the functional activity of the RN-tre protein. These chemicals exert their effects by acting on the specific signaling pathways that the RN-tre protein is involved in. For instance, Forskolin and Cilostazol are known to affect the cAMP-dependent pathway, which is one of the pathways RN-tre is involved in. By increasing the cAMP level in the cell, these compounds indirectly enhance the activity of RN-tre.
On the other hand, compounds like LY294002 and Wortmannin act on the PI3K/Akt pathway, another pathway involving RN-tre. T Similarly, compounds like U0126 and PD98059 act on the MAPK signaling pathway.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a potent adenylate cyclase activator, promoting the production of cyclic AMP (cAMP). Given that RN-tre is involved in the cAMP-dependent pathway, Forskolin, by enhancing the cAMP level, can indirectly enhance RN-tre activity. | ||||||
Cilostazol | 73963-72-1 | sc-201182 sc-201182A | 10 mg 50 mg | $109.00 $322.00 | 3 | |
Cilostazol is a phosphodiesterase III inhibitor which prevents the degradation of cAMP. Increased cAMP levels can indirectly enhance RN-tre activation in the cAMP-dependent signaling pathway. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective phosphodiesterase inhibitor. It prevents the breakdown of cAMP and cyclic GMP (cGMP), thereby indirectly enhancing RN-tre activity via the cAMP-dependent pathway. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA (Phorbol 12-myristate 13-acetate) is a potent activator of protein kinase C (PKC). PKC plays a role in several signaling pathways, including those RN-tre is involved in. Hence, PMA can indirectly enhance RN-tre activity. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases, including PKC. By inhibiting PKC, it can alter the dynamics of the pathways RN-tre is involved in, thereby indirectly enhancing RN-tre activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a selective inhibitor of MEK1. Like U0126, it can indirectly enhance RN-tre activity via the MAPK signaling pathway. | ||||||
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $208.00 $270.00 | 29 | |
Akt Inhibitor VIII is a potent inhibitor of Akt1/2/3. Given that RN-tre is involved in the PI3K/Akt pathway, this inhibitor can indirectly enhance RN-tre activity by altering the dynamics of this pathway. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a potent inhibitor of protein tyrosine kinases. By inhibiting these kinases, it can alter the dynamics of the pathways RN-tre is involved in, thereby indirectly enhancing RN-tre activity. | ||||||