Ribosomal Protein L10a Activators refer to a class of chemicals that can indirectly influence the function of the RPL10A protein, a ribosomal protein that plays a role in protein synthesis and ribosome biogenesis. This diverse class of chemicals includes mTOR inhibitors, protein synthesis inhibitors, DNA and RNA synthesis inhibitors, dihydrofolate reductase inhibitors, thymidylate synthase inhibitors, ribonucleotide reductase inhibitors, and purine synthesis inhibitors. These chemicals do not directly interact with RPL10A, but they can affect the cellular pathways and processes in which RPL10A is involved.
These chemicals can alter a range of cellular processes, including mTOR signaling, protein synthesis, DNA and RNA synthesis, nucleotide biosynthesis, and purine synthesis. Through these actions, they can indirectly modulate the function of RPL10A in ribosome biogenesis and protein synthesis. By inhibiting these processes, these chemicals may lead to increased cellular reliance on existing ribosomal proteins, potentially enhancing the functional role of RPL10A. It is through this increased dependence on the ribosome biogenesis machinery and protein synthesis pathways that these chemicals can indirectly activate RPL10A.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
A mTOR inhibitor that can affect mTOR signaling pathway, potentially impacting RPL10A's role in ribosome biogenesis. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
Torin1 is a potent inhibitor of mTORC1 and mTORC2 which may indirectly influence the role of RPL10A in ribosome biogenesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
An inhibitor of protein biosynthesis in eukaryotes, it blocks the translational step, indirectly affecting RPL10A's role in protein synthesis. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
It inhibits DNA and RNA synthesis, affecting the general transcriptional machinery and indirectly affecting RPL10A's role in translation. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
A protein synthesis inhibitor that causes premature chain termination during translation, potentially impacting RPL10A. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
It inhibits protein synthesis by blocking peptide bond formation, potentially affecting RPL10A's role. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
It inhibits dihydrofolate reductase, affecting nucleotide biosynthesis and potentially RPL10A's role in ribosome biogenesis. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
An antimetabolite that inhibits thymidylate synthase, leading to inhibited DNA synthesis and potentially affecting RPL10A's role in ribosome biogenesis. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
It inhibits ribonucleotide reductase, affecting DNA synthesis and potentially RPL10A's role in ribosome biogenesis. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $440.00 $900.00 $1400.00 $2502.00 | ||
It inhibits protein synthesis by interfering with the action of 40S ribosome, potentially affecting RPL10A. | ||||||