RhCE Activators
RhCE Modulators includes various compounds that can indirectly influence the expression or function of Rh blood group CcEe antigens, primarily through their effects on erythrocyte development, membrane integrity, or ion transport. Since RhCE antigens are transmembrane proteins on red blood cells, their modulation is generally not direct but rather occurs through pathways affecting erythrocyte biology.
Erythropoietin (EPO) is a primary regulator of erythropoiesis, the process of red blood cell production. By stimulating erythropoiesis, EPO can affect the expression of RhCE antigens as new erythrocytes are formed. Hydroxyurea, used in sickle cell disease, influences erythrocyte characteristics and may indirectly affect the expression or function of RhCE antigens. Nutritional supplements essential for erythropoiesis, such as iron, folic acid, and vitamin B12, can also influence RhCE expression by supporting the production and development of healthy red blood cells. Zinc supplements play a role in maintaining membrane integrity, which is crucial for the proper functioning of membrane proteins like RhCE antigens. Corticosteroids like Prednisone and immunosuppressants such as Cyclosporine A and Dexamethasone can modulate erythropoiesis and immune responses, impacting the expression and function of RhCE antigens.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is important for DNA synthesis and red blood cell production, potentially influencing RhCE expression. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Vitamin B12 is crucial for erythropoiesis and might indirectly influence RhCE antigen expression. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc plays a role in maintaining membrane integrity, potentially affecting RhCE antigen functionality. | ||||||
Prednisone | 53-03-2 | sc-205816 sc-205816A sc-205816B | 1 g 5 g 25 g | $41.00 $133.00 $663.00 | 2 | |
Corticosteroids can influence erythropoiesis and immune responses, potentially impacting RhCE antigens. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that might affect erythrocyte membrane characteristics, indirectly influencing RhCE antigens. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone can affect erythropoiesis and immune modulation, potentially impacting RhCE antigens. | ||||||
Danazol | 17230-88-5 | sc-203021 sc-203021A | 100 mg 250 mg | $90.00 $233.00 | 3 | |
Danazol, used in some hematological conditions, might influence erythropoiesis and RhCE expression. | ||||||
Captopril | 62571-86-2 | sc-200566 sc-200566A | 1 g 5 g | $48.00 $89.00 | 21 | |
ACE inhibitors can affect blood pressure and kidney function, indirectly impacting erythropoiesis and RhCE expression. | ||||||
DL-α-Tocopherol | 10191-41-0 | sc-294383 sc-294383A sc-294383B sc-294383C | 5 g 25 g 100 g 500 g | $25.00 $51.00 $122.00 $320.00 | 3 | |
Antioxidants protect cell membranes from oxidative damage, potentially influencing RhCE antigen stability. | ||||||