Date published: 2025-10-21

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Ref-1 Antibodies

Santa Cruz Biotechnology features a diverse variety of Ref-1 monoclonal antibodies for advanced research in cellular signaling and redox regulation. Ref-1 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Ref-1, also known as APE1, plays a critical role in DNA repair and transcriptional regulation, influencing cellular responses to oxidative stress. Its function is essential for maintaining genomic stability and regulating the expression of various genes involved in cell survival and proliferation. Given its involvement in key cellular processes, Ref-1 is a significant target for understanding cancer biology and therapeutic interventions. Researchers worldwide rely on Ref-1 monoclonal antibodies to investigate DNA repair mechanisms and cellular responses to oxidative damage. Understanding Ref-1's role in various pathways helps advance knowledge in cancer research and potential treatment strategies. The extensive applications of Ref-1 monoclonal antibodies make them essential tools for exploring cellular mechanisms in both normal and disease states. Santa Cruz Biotechnology monoclonal antibodies for Ref-1 continue to support breakthrough discoveries in cellular biology and therapeutic research.

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Ref-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Ref-1 Antibody (C-4)

sc-17774mouse IgG2b κ1-300 (h)WB, IP, IF, IHC(P)m, r, h
63
(20)

Ref-1 Antibody (H-6)

sc-55498mouse IgG2a κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
11
(4)

Ref-1 Antibody (15)

sc-136057mouse IgG13-142 (h)WB, IP, IFm, r, h and canine
1
(2)

Ref-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ref-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400932-KO-2hGene KnockoutGFP0
(1)

Ref-1 HDR Plasmid (h2)

sc-400932-HDR-2hHomology Directed RepairPuromycin0
(1)

Ref-1 Double Nickase Plasmid (h)

sc-400932-NIChGene KnockoutPuromycin0
(1)

Ref-1 Double Nickase Plasmid (h2)

sc-400932-NIC-2hGene KnockoutPuromycin0
(1)

Ref-1 CRISPR/Cas9 KO Plasmid (m)

sc-419148mGene KnockoutGFP0
(0)

Ref-1 HDR Plasmid (m)

sc-419148-HDRmHomology Directed RepairPuromycin0
(0)

Ref-1 Double Nickase Plasmid (m)

sc-419148-NICmGene KnockoutPuromycin0
(0)

Ref-1 Double Nickase Plasmid (m2)

sc-419148-NIC-2mGene KnockoutPuromycin0
(0)

Ref-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ref-1 CRISPR Activation Plasmid (h)

sc-400932-ACThGene ActivationPuro, Blast, Hygro0
(1)

Ref-1 CRISPR Activation Plasmid (h2)

sc-400932-ACT-2hGene ActivationPuro, Blast, Hygro0
(1)

Ref-1 Lentiviral Activation Particles (h)

sc-400932-LAChGene ActivationPuro, Blast, Hygro0
(1)

Ref-1 Lentiviral Activation Particles (h2)

sc-400932-LAC-2hGene ActivationPuro, Blast, Hygro0
(1)

Ref-1 CRISPR Activation Plasmid (m)

sc-419148-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Ref-1 CRISPR Activation Plasmid (m2)

sc-419148-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Ref-1 Lentiviral Activation Particles (m)

sc-419148-LACmGene ActivationPuro, Blast, Hygro0
(0)

Ref-1 Lentiviral Activation Particles (m2)

sc-419148-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Ref-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Ref-1 siRNA (h)

sc-29470hGene SilencingN/A
8
(1)

Ref-1 shRNA Plasmid (h)

sc-29470-SHhGene SilencingPuromycin
8
(1)

Ref-1 shRNA (h) Lentiviral Particles

sc-29470-VhGene SilencingPuromycin
8
(1)

Ref-1 siRNA (m)

sc-36401mGene SilencingN/A
1
(0)

Ref-1 shRNA Plasmid (m)

sc-36401-SHmGene SilencingPuromycin
1
(0)

Ref-1 shRNA (m) Lentiviral Particles

sc-36401-VmGene SilencingPuromycin
1
(0)

Ref-1 siRNA (r)

sc-72399rGene SilencingN/A0
(0)

Ref-1 shRNA Plasmid (r)

sc-72399-SHrGene SilencingPuromycin0
(0)

Ref-1 shRNA (r) Lentiviral Particles

sc-72399-VrGene SilencingPuromycin0
(0)