Ref-1 Antibody (15): sc-136057
- Ref-1 Antibody (15) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 3-142 of Ref-1 of human origin
- recommended for detection of Ref-1 of mouse, rat, human and canine origin by WB, IP and IF; not recommended for IP
- See Ref-1 (C-4): sc-17774 for Ref-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Ref-1 Antibody (15). This work is in progress.
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SEE ALSO...
Ref-1 Antibody (15) is a mouse monoclonal IgG1 antibody that recognizes Ref-1 in mouse, rat, human, and canine samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Ref-1, also known as redox factor 1, plays a crucial role in regulating transcription factor activity by modulating redox state, which maintains proper gene expression. Ref-1 primarily localizes in the nucleus, functioning as a redox regulator with DNA repair capabilities, highlighting Ref-1′s importance in cellular responses to oxidative stress and DNA damage. Anti-Ref-1 antibody (15) enables research into how Ref-1 interacts with and activates transcription factors like Fos and Jun through reversible oxidation of a conserved cysteine residue, underscoring Ref-1′s significance in cellular signaling pathways. By restoring DNA binding activity in transcription factors, Ref-1 ensures fine-tuned gene expression in response to environmental changes, making Ref-1 vital for cellular homeostasis and prevention of diseases related to dysregulated gene expression. Anti-Ref-1 antibody (15) serves as an essential tool for studying gene regulation mechanisms and cellular responses to oxidative stress.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ref-1 Antibody (15) | sc-136057 | 50 µg/0.5 ml | $322.00 |