Date published: 2025-12-5

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Ref-1 Inhibitors

Ref-1 inhibitors represent a distinctive class of chemical compounds designed with precision to modulate specific cellular processes through interaction with a key target protein, Ref-1 (Redox Factor-1). Within the intricate milieu of cellular dynamics, Ref-1 assumes a multifunctional role, playing a pivotal part in the regulation of cellular responses by serving as a critical component in DNA repair and gene expression processes. The nuanced design of Ref-1 inhibitors entails a strategic molecular architecture, allowing these compounds to bind specifically to Ref-1, thereby disrupting its normative functions. This disruptive interaction positions Ref-1 inhibitors as influencers of cellular signaling pathways and molecular cascades intricately linked to DNA repair and gene regulation. The deliberate targeting of Ref-1 by these inhibitors opens avenues for the modulation of cellular responses to various environmental stressors and external stimuli. The study of Ref-1 inhibitors stands as a dynamic field of active research, driven by the scientific quest to unravel the intricate mechanisms governing cellular processes. By probing the effects of Ref-1 inhibitors, researchers aim to decipher the broader implications of manipulating Ref-1's activity, offering valuable insights into the interconnected molecular pathways that underpin cellular responses to diverse stimuli. The strategic engagement with Ref-1 inhibitors underscores a meticulous approach to understanding and influencing fundamental cellular processes at the molecular level.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

DNA Base Excision Repair Pathway Inhibitor Inhibitor

6960-45-8sc-202588
1 g
$92.00
(1)

DNA Base Excision Repair Pathway Inhibitor functions by disrupting the intricate network of DNA repair mechanisms. It selectively targets key enzymes involved in the base excision repair process, altering their binding affinity and catalytic efficiency. This compound's unique ability to modulate enzyme interactions leads to a significant impact on the kinetics of DNA repair, providing insights into the molecular dynamics of genomic stability and cellular response to DNA damage.

Trichloroethylene

79-01-6sc-251310
sc-251310A
500 ml
1 L
$65.00
$108.00
(0)

Disrupts REF-1's DNA binding activity, impeding its role in transcriptional regulation and DNA repair.

JNK Inhibitor V

345987-15-7sc-202672A
sc-202672
1 mg
5 mg
$60.00
$169.00
3
(1)

Blocks REF-1's endonuclease activity, impairing DNA repair and promoting apoptosis in cancer cells.

MLN7243

1450833-55-2sc-507338
5 mg
$340.00
(0)

Suppresses the ubiquitin-proteasome system, impacting REF-1's stability and reducing its activity.