RBQ-3 inhibitors are designed to modulate the activity of RBQ-3, a specific protein or enzyme within cellular pathways. These inhibitors are meticulously engineered to bind selectively to the active site of RBQ-3, thereby altering its function and influencing downstream cellular processes. The development of RBQ-3 inhibitors often involves a sophisticated understanding of the three-dimensional structure of the target protein, allowing for precise design and optimization of small molecules to interact with the catalytic or regulatory domains of RBQ-3.
The mechanism of action of RBQ-3 inhibitors is intricately linked to their ability to disrupt the normal functioning of RBQ-3, leading to a cascade of molecular events that can impact various cellular functions. The binding of these inhibitors to RBQ-3 can result in the inhibition of enzymatic activity, interference with substrate recognition, or modulation of protein-protein interactions essential for normal cellular signaling. As a consequence, RBQ-3 inhibitors hold immense potential as valuable tools for unraveling the intricacies of cellular pathways and as leads for the development of novel compounds with potential applications in various scientific and biomedical fields.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pifithrin-α hydrobromide | 63208-82-2 | sc-45050 sc-45050A | 5 mg 25 mg | $118.00 $287.00 | 36 | |
Can inhibit p53 by blocking its transcriptional activity, potentially reducing DNA repair and apoptosis induction. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Can inhibit the interaction between p53 and MDM2, leading to stabilization and activation of p53. | ||||||
p53 Activator III, RITA | 213261-59-7 | sc-202753 sc-202753A sc-202753B sc-202753C | 1 mg 10 mg 100 mg 500 mg | $110.00 $268.00 $1533.00 $5103.00 | 9 | |
Can bind to p53 and prevent its interaction with MDM2, which stabilizes p53. | ||||||
Tenovin-6 | 1011557-82-6 | sc-224296 sc-224296A | 1 mg 5 mg | $272.00 $1214.00 | 9 | |
Can increase p53 levels by inhibiting SIRT1 and SIRT2, leading to activation of p53 pathways. | ||||||
PRIMA-1 | 5608-24-2 | sc-200927 sc-200927A | 5 mg 25 mg | $102.00 $408.00 | 1 | |
Can reactivate mutant forms of p53, restoring its DNA-binding and tumor suppressor functions. | ||||||
CP 31398 dihydrochloride | 259199-65-0 | sc-205270 sc-205270A | 10 mg 50 mg | $107.00 $425.00 | ||
Can stabilize the active conformation of p53, potentially restoring its function in cells with mutant p53. | ||||||
MIRA-1 | 72835-26-8 | sc-204087 sc-204087A | 10 mg 50 mg | $116.00 $443.00 | 1 | |
Can modify mutant p53, potentially restoring its wild-type conformation and function. | ||||||
2-Vinyl-4-quinazolinol | 91634-12-7 | sc-308709 | 250 mg | $143.00 | ||
Can stabilize p53 tetramers, enhancing DNA binding and transcriptional activity of p53. | ||||||
NSC-59984 | 803647-40-7 | sc-507310 | 10 mg | $230.00 | ||
Can restore wild-type p53 signaling in cells with mutant p53, leading to cell cycle arrest and apoptosis. | ||||||