RAR gamma Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CD 2665 | 170355-78-9 | sc-293988 sc-293988A | 10 mg 50 mg | $238.00 $974.00 | 2 | |
CD 2665 functions as a selective RAR gamma modulator, characterized by its unique ability to stabilize receptor dimers through specific hydrogen bonding interactions. This compound exhibits a distinctive hydrophobic core that facilitates enhanced binding affinity, promoting effective signal transduction. Its structural rigidity contributes to slower reaction kinetics, allowing for prolonged receptor activation. Additionally, CD 2665's unique steric properties influence its interaction with co-regulators, further diversifying its biological impact. | ||||||
BMS 453 | 166977-43-1 | sc-311294 | 10 mg | $189.00 | 1 | |
BMS 453 acts as a selective RAR gamma modulator, distinguished by its capacity to engage in unique electrostatic interactions that enhance receptor affinity. This compound features a flexible molecular framework, allowing for dynamic conformational changes that optimize binding efficiency. Its specific isomeric forms exhibit varied reactivity profiles, influencing downstream signaling pathways. Furthermore, BMS 453's solubility characteristics facilitate its interaction with lipid membranes, impacting cellular uptake and distribution. | ||||||
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $54.00 $245.00 | 6 | |
Bexarotene is a synthetic retinoid and RARγ agonist, primarily used in cancer therapy. Although traditionally considered an activator, the dual nature of retinoids can lead to context-dependent actions. In certain cellular environments or concentrations, Bexarotene may exhibit inhibitory effects on RARγ, possibly through interference with co-regulatory proteins or induction of negative feedback loops. | ||||||
MM 11253 | 345952-44-5 | sc-361255 sc-361255A | 10 mg 50 mg | $468.00 $2000.00 | 2 | |
MM11253 is a chemical compound with reported inhibitory effects on RARγ. Its potential as an RARγ inhibitor suggests interference with retinoic acid-mediated signaling pathways. MM11253 provides researchers with a tool to explore the specific contributions of RARγ to cellular processes and to decipher its role in development, differentiation, and disease. | ||||||
CD 1530 | 107430-66-0 | sc-203871 sc-203871A | 10 mg 50 mg | $204.00 $816.00 | ||
CD1530 is a synthetic retinoid with reported inhibitory effects on RARγ. As a potential RARγ inhibitor, CD1530 may interfere with retinoic acid binding, modulating downstream signaling cascades associated with RARγ activity. This compound serves as a valuable pharmacological tool for researchers aiming to dissect the specific contributions of RARγ to cellular processes and explore its implications in various contexts, including development, differentiation, and disease. | ||||||