RARγ/Retinoic Acid Receptor γ Antibody (H-6): sc-398065

RARγ Antibody (H-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects RAR gamma protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-RARγ antibody (H-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RAR gamma protein plays a crucial role in regulating gene expression during vertebrate development and tissue differentiation, acting as a nuclear transcription factor that modulates retinoid effects, which are metabolites of vitamin A. RARγ interacts with retinoic acid, leading to conformational changes that facilitate DNA binding and target gene transcription. This process influences cell growth, differentiation, and apoptosis, making RARγ essential for proper cellular function and development. RARγ expression is tissue-specific, with significant roles in skin and lung tissues, where expression can be altered in pathological conditions such as lung cancer. Human RARγ gene is located on chromosome 12q13, highlighting its importance in genetic regulation and potential implications in disease mechanisms.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RARγ/Retinoic Acid Receptor γ Antibody (H-6) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-RARγ/Retinoic Acid Receptor γ Antibody (H-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RARγ/Retinoic Acid Receptor γ Antibody (H-6) Specifications

Alternate Product Name: RARγ

Product Clone Name: H-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 417-454

Epitope Target: RARγ

Epitope Species: human

Product Reactivity/Detection: RARγ1 and RARγ2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for RARγ/Retinoic Acid Receptor γ Antibody (H-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent

The preferred RARγ/Retinoic Acid Receptor γ antibody is RARγ/Retinoic Acid Receptor γ Antibody (G-1): sc-7387.