Molecular structure of CD 1530, CAS Number: 107430-66-0
CD 1530 (CAS 107430-66-0)
Alternate Names:
4-[7-(1-adamantyl)-6-hydroxynaphthalen-2-yl]benzoic acid;
Application:
CD 1530 is a potent and selective RARγ agonist
CAS Number:
107430-66-0
Purity:
≥98%
Molecular Weight:
398.49
Molecular Formula:
C27H26O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
CD 1530 is a potent and selective RARγ agonist which is noted to activate transcriptional activity. CD 1530 is an activator of RAR alpha and RAR beta.
CD 1530 (CAS 107430-66-0) References
- Therapeutic applications for ligands of retinoid receptors. | Thacher, SM., et al. 2000. Curr Pharm Des. 6: 25-58. PMID: 10637371
- Clinically applicable antianginal agents suppress osteoblastic transformation of myogenic cells and heterotopic ossifications in mice. | Yamamoto, R., et al. 2013. J Bone Miner Metab. 31: 26-33. PMID: 23011467
- Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes. | Murholm, M., et al. 2013. BMC Cell Biol. 14: 41. PMID: 24059847
- Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide. | Tang, XH., et al. 2014. Proc Natl Acad Sci U S A. 111: 8907-12. PMID: 24927566
- Selective Retinoic Acid Receptor γ Agonists Promote Repair of Injured Skeletal Muscle in Mouse. | Di Rocco, A., et al. 2015. Am J Pathol. 185: 2495-504. PMID: 26205250
- Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitrox. | Webb, S., et al. 2016. Stem Cell Res Ther. 7: 45. PMID: 27001426
- A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease. | Trasino, SE., et al. 2016. J Mol Med (Berl). 94: 1143-1151. PMID: 27271256
- A new class of synthetic retinoid antibiotics effective against bacterial persisters. | Kim, W., et al. 2018. Nature. 556: 103-107. PMID: 29590091
- Retinoic Acid Receptor Agonists Suppress Muscle Fatty Infiltration in Mice. | Shirasawa, H., et al. 2021. Am J Sports Med. 49: 332-339. PMID: 33428447
- Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success. | Huemer, M., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 33574060
- Dysregulated Retinoic Acid Signaling in the Pathogenesis of Pseudoexfoliation Syndrome. | Zenkel, M., et al. 2022. Int J Mol Sci. 23: PMID: 35682657
Inhibitor of:
RAR gamma.Activator of:
RAR alpha, RAR beta, and RAR gamma.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD 1530, 10 mg | sc-203871 | 10 mg | $208.00 | |||
| US: Only available in the US | ||||||
CD 1530, 50 mg | sc-203871A | 50 mg | $832.00 | |||
| US: Only available in the US | ||||||