RAR beta Activators
Items 1 to 10 of 15 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TTNPB | 71441-28-6 | sc-203303 sc-203303A sc-203303B | 10 mg 25 mg 50 mg | $206.00 $340.00 $562.00 | 20 | |
TTNPB is a synthetic retinoid and a potent RAR agonist. It directly activates RARβ, promoting its transcriptional activity and influencing downstream pathways related to cell growth and apoptosis. TTNPB has been extensively studied for its effects on cancer and differentiation processes. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
ATRA is a natural derivative of vitamin A and a ligand for RARβ. It directly activates RARβ by binding to its receptor, leading to transcriptional activation of target genes involved in cellular differentiation and apoptosis. | ||||||
AM 580 | 102121-60-8 | sc-203505 sc-203505A | 5 mg 25 mg | $97.00 $382.00 | 2 | |
AM 580 is a selective RAR beta agonist characterized by its unique ability to induce receptor dimerization, enhancing its interaction with retinoic acid response elements. This compound demonstrates a distinct kinetic profile, exhibiting rapid binding kinetics that facilitate swift cellular responses. Its specific molecular interactions with the receptor's ligand-binding domain promote a conformational shift, optimizing downstream signaling cascades. Additionally, AM 580's solubility in various solvents enhances its versatility in experimental settings. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $70.00 $416.00 $3060.00 $5610.00 $145.00 | 10 | |
9-cis-retinoic acid is an isomer of ATRA and serves as a ligand for RARs, including RARβ. It directly activates RARβ, influencing the expression of target genes associated with cellular differentiation and apoptosis. | ||||||
CD 437 | 125316-60-1 | sc-202527 | 5 mg | $121.00 | ||
CD437 is a synthetic retinoid and a selective RAR agonist. It directly activates RARβ, promoting its transcriptional activity and influencing downstream pathways related to cell growth and apoptosis. | ||||||
Adapalene | 106685-40-9 | sc-203803 sc-203803A | 10 mg 50 mg | $65.00 $325.00 | 2 | |
Adapalene is a synthetic retinoid that has been reported to activate RARβ. Although its primary use is in dermatology for the treatment of acne, Adapalene's influence on RARβ may contribute to its effects on keratinocyte differentiation and anti-inflammatory properties. | ||||||
BMS 961 | 185629-22-5 | sc-362717 sc-362717A | 10 mg 50 mg | $306.00 $1020.00 | ||
BMS 961 is a potent RAR beta agonist known for its ability to stabilize receptor conformations, leading to enhanced transcriptional activity. It exhibits unique binding dynamics, allowing for prolonged receptor engagement and modulation of gene expression. The compound's interactions with the receptor's allosteric sites facilitate distinct signaling pathways, contributing to its efficacy. Furthermore, BMS 961's physicochemical properties enable effective solvation in diverse environments, supporting its experimental applications. | ||||||
CD 1530 | 107430-66-0 | sc-203871 sc-203871A | 10 mg 50 mg | $204.00 $816.00 | ||
HX600 (CD1530) is a synthetic RAR agonist that selectively activates RARs, including RARβ. It functions as a ligand for RARβ, leading to the activation of RARβ-dependent signaling pathways involved in cellular differentiation and apoptosis. | ||||||
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $54.00 $245.00 | 6 | |
Bexarotene is a synthetic rexinoid and a selective agonist for RARs. It has been shown to activate RARβ and is studied in the research of cutaneous T-cell lymphoma. Bexarotene influences RARβ-dependent gene expression, affecting cell cycle regulation and differentiation. | ||||||
CH 55 | 110368-33-7 | sc-203884 sc-203884A | 10 mg 50 mg | $138.00 $587.00 | ||
Ch55 is a synthetic RAR agonist that specifically targets RARβ. It acts as a ligand for RARβ, leading to the activation of RARβ-dependent signaling pathways involved in cellular differentiation and apoptosis. | ||||||