RAI3 Activators represent a class of chemical compounds designed and studied for their ability to modulate the activity of the Retinoic Acid-Inducible Gene 3 (RAI3) protein. RAI3, also known as GPRC5A, is a transmembrane protein that belongs to the G protein-coupled receptor (GPCR) family. It plays a crucial role in various cellular processes, including cell growth, differentiation, and signal transduction. The activation of RAI3 can lead to a cascade of intracellular events that ultimately influence gene expression and impact cell behavior.
Chemical compounds categorized as RAI3 activators are typically small molecules that have been developed through extensive medicinal chemistry efforts. These molecules are designed to bind selectively to the RAI3 receptor and trigger a conformational change that results in its activation. The activation of RAI3, in turn, can lead to the activation of downstream signaling pathways, such as those involving G proteins and intracellular second messengers. Researchers have been particularly interested in understanding the precise mechanisms by which RAI3 activation influences cellular processes and gene expression, as this knowledge can have important implications in various biological contexts.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a natural derivative of vitamin A and acts as a ligand for nuclear receptors, such as retinoic acid receptors (RARs). It activates RAI3 gene expression via RAR binding and RARE-mediated transcription. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
9-cis-retinoic acid is an isomer of retinoic acid that activates RAI3 gene expression by binding to retinoic acid receptors (RARs) and promoting RAI3 transcription through RAREs. | ||||||
4-Hydroxyphenylretinamide | 65646-68-6 | sc-200900 sc-200900A | 5 mg 25 mg | $104.00 $315.00 | ||
4-Hydroxyphenylretinamide, a synthetic retinoid, activates RAI3 gene expression by binding to retinoid receptors (e.g., RARs) and promoting RAI3 transcription through RARE binding. | ||||||
AM 80 | 94497-51-5 | sc-203816 sc-203816A | 10 mg 50 mg | $155.00 $620.00 | 1 | |
AM 80 is a synthetic retinoid that activates RAI3 gene expression through RAR binding, leading to increased RAI3 transcription via RAREs. | ||||||