Rab L2B, also referred to as Rab-like protein 2B, is a member of the Rab protein family, which consists of small GTPases involved in intracellular vesicle transport and membrane trafficking. These proteins act as molecular switches cycling between an active GTP-bound state and an inactive GDP-bound state. The Rab family of proteins is highly conserved across eukaryotic species and plays a pivotal role in ensuring that vesicles are delivered to the correct locations within the cell.The specific functions of Rab L2B within the Rab protein family are not as well characterized as those of other Rab proteins. However, like other Rabs, Rab L2B likely participates in the regulation of vesicle trafficking processes, such as endocytosis, exocytosis, and the recycling of membrane components. This can include the shuttling of cargo between various organelles like the endoplasmic reticulum, Golgi apparatus, endosomes, lysosomes, and the plasma membrane.
Rab L2B, by virtue of its potential involvement in these processes, could play a role in maintaining cellular homeostasis, coordinating the secretion of proteins, and regulating the response of cells to external signals. The precise localization and interaction partners of Rab L2B within cells would provide more insight into its specific functional roles.Research into Rab L2B may reveal its involvement in particular cellular pathways or disorders, as Rab proteins are often implicated in diseases such as cancer, neurodegenerative conditions, and immune system dysfunctions.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt | 94825-44-2 | sc-202639 | 10 mg | $456.00 | ||
A non-hydrolyzable GTP analog, can activate GTPases like Rab proteins, potentially impacting Rab L2B function. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts vesicle formation from the Golgi, potentially impacting Rab L2B-mediated transport. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubules, affecting vesicle transport and potentially influencing Rab L2B activity. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Affects intracellular transport and pH, potentially influencing Rab L2B-mediated vesicle trafficking. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits phosphatidylinositol 3-kinase (PI3K), impacting vesicle trafficking and possibly Rab L2B function. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Inhibits dynamin, affecting vesicle scission and potentially Rab L2B-mediated processes. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Disrupts actin filaments, potentially affecting vesicle movement and Rab L2B activity. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
A Cdc42 GTPase inhibitor, potentially affecting pathways interacting with Rab L2B. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, indirectly affecting various cellular signaling pathways, including those involving Rab proteins. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Disrupts microtubules, potentially affecting Rab L2B-dependent vesicle transport. |