Protor-2 Inhibitors
Protor-2 inhibitors belong to a specialized category of chemical compounds that primarily target a specific protein known as Protor-2. These inhibitors are designed with a precise molecular structure and mechanism of action to modulate the activity of Protor-2 within cellular pathways. Protor-2, short for Protein Observed with Rictor-2, is a relatively newly discovered protein that plays a crucial role in the regulation of various cellular processes. It is a part of the mTORC2 (mammalian target of rapamycin complex 2) signaling pathway, a fundamental intracellular pathway involved in cell growth, proliferation, and survival. Protor-2, as a component of mTORC2, acts as a scaffold protein, facilitating the proper assembly and function of this complex.
Protor-2 inhibitors are meticulously designed molecules that specifically interfere with the function of Protor-2, disrupting its ability to interact with other proteins within the mTORC2 pathway. This targeted interference can have downstream effects on various cellular processes and signaling cascades, potentially leading to alterations in cell growth, differentiation, and metabolism. Researchers are keenly interested in studying Protor-2 inhibitors due to their potential to uncover the intricate details of mTORC2 signaling and its impact on various cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $57.00 $172.00 | 8 | |
PP242 is an ATP-competitive inhibitor of mTOR kinase activity, which can indirectly affect PRR5L function by inhibiting the mTORC2 complex. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $245.00 | 7 | |
Torin 1 is another selective ATP-competitive inhibitor of mTOR that can disrupt PRR5L's action by targeting mTORC2 as well as mTORC1. | ||||||
KU 0063794 | 938440-64-3 | sc-361219 | 10 mg | $209.00 | ||
Ku-0063794 is a dual mTORC1 and mTORC2 inhibitor that can suppress the signaling pathways involving PRR5L. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
AZD8055 is a potent ATP-competitive mTOR inhibitor that blocks the activity of both mTORC1 and mTORC2, potentially influencing PRR5L's role in these complexes. | ||||||
WYE-354 | 1062169-56-5 | sc-364652 sc-364652A | 10 mg 50 mg | $286.00 $1200.00 | ||
WYE-354 is designed to inhibit mTOR kinase activity, thereby affecting PRR5L through the mTOR signaling cascade. | ||||||
OSI-027 | 936890-98-1 | sc-364557 sc-364557A | 10 mg 50 mg | $437.00 $1186.00 | 1 | |
OSI-027 is a selective ATP-competitive mTOR inhibitor, impacting both mTORC1 and mTORC2 functions and thus the activities of PRR5L. | ||||||
Palomid 529 | 914913-88-5 | sc-364563 sc-364563A | 10 mg 50 mg | $300.00 $1000.00 | ||
Palomid 529 is a PI3K/Akt/mTOR pathway inhibitor, which can indirectly affect PRR5L through modulation of this pathway. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $33.00 $131.00 | 3 | |
PI-103 is a small molecule inhibitor of PI3K and mTOR, suggesting it may influence PRR5L by these pathways' modulation. | ||||||
INK 128 | 1224844-38-5 | sc-364511 sc-364511A | 5 mg 50 mg | $321.00 $1835.00 | ||
INK 128 is a selective ATP competitive inhibitor of mTORC1/2, potentially affecting PRR5L's associated functions. | ||||||
GDC-0980 | 1032754-93-0 | sc-364499 sc-364499A | 5 mg 50 mg | $347.00 $1428.00 | ||
GDC-0980 is a PI3K and mTOR inhibitor, which can alter the activity of PRR5L by inhibiting pathways in which it is involved. | ||||||