PQLC1 Activators
Protein PQLC1, encoded by the PQLC1 gene, is a lysosomal amino acid transporter associated with a rare autosomal recessive lysosomal storage disease called lysosomal amino acid transport disorder (LAAT1). PQLC1 is integral to the proper functioning of lysosomes, which are cellular organelles responsible for breaking down and recycling various biomolecules.
PQLC1 is known to play a critical role in facilitating the efflux of amino acids from the lysosome into the cytosol, thereby maintaining amino acid homeostasis within the cell. By transporting amino acids out of the lysosome, PQLC1 ensures that they are available for protein synthesis and other metabolic processes. The transporter activity of PQLC1 is believed to be crucial in conditions where lysosomal degradation of proteins is upregulated, such as during nutrient starvation or autophagy, a process where cells degrade and recycle their own components.Mutations in the PQLC1 gene can lead to the accumulation of amino acids within lysosomes, causing cellular dysfunction and contributing to the pathology of lysosomal storage disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
PQQ, a redox cofactor, might influence PQLC1 by participating in redox reactions and affecting signaling pathways potentially linked to PQLC1's function. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
NAC, known for its antioxidant properties, could indirectly affect PQLC1 activity by modulating oxidative stress and redox signaling. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $76.00 $2050.00 | 8 | |
Glutathione, a key antioxidant, may influence PQLC1 indirectly through its role in maintaining cellular redox balance. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
As an antioxidant, Alpha-Lipoic Acid could impact PQLC1 activity indirectly by affecting redox-sensitive signaling pathways. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10, involved in mitochondrial electron transport, might affect PQLC1 indirectly by influencing mitochondrial function and redox status. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol affects gene expression and oxidative stress response, potentially impacting PQLC1 activity if linked to these mechanisms. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, known for its role in activating antioxidant response elements, could indirectly influence PQLC1 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, with its anti-inflammatory and antioxidant properties, might affect PQLC1 activity indirectly through cellular signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a polyphenol with antioxidant properties, might modulate PQLC1 activity indirectly through its impact on redox balance and signaling. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Vitamin C, an antioxidant, could influence PQLC1 indirectly through its role in redox regulation and cellular protection. | ||||||