Date published: 2026-4-30

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PPAR beta Inhibitors

Santa Cruz Biotechnology now offers a broad range of PPAR beta Inhibitors for use in various applications. PPAR beta Inhibitors focus on the modulation of the peroxisome proliferator-activated receptor beta (PPARβ), a nuclear receptor involved in regulating fatty acid metabolism, cellular proliferation, and differentiation, exclusively in research settings. These inhibitors are critical in scientific studies aiming to dissect the role of PPARβ in cellular processes, providing insights into its function in energy homeostasis and lipid metabolism. By inhibiting PPARβ, researchers can study its impact on gene expression and the physiological consequences of altering this pathway, helping to clarify the complex network of metabolic regulation. The inhibition of PPARβ is particularly valuable in research focused on understanding the molecular mechanisms that govern cell differentiation and metabolic rate adjustments in response to varying environmental conditions. These studies contribute significantly to our broader understanding of cellular metabolism and can help identify potential regulatory mechanisms that influence cellular function and development. Additionally, PPAR beta Inhibitors are used in developmental biology and systems biology to explore how changes in metabolic signaling can affect overall organismal physiology. By providing these inhibitors, Santa Cruz Biotechnology supports cutting-edge research that explores fundamental biological processes and aids in the advancement of general scientific knowledge regarding cellular metabolism and regulation. View detailed information on our available PPAR beta Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

GSK 0660

1014691-61-2sc-203985
sc-203985A
10 mg
50 mg
$175.00
$709.00
14
(1)

GSK0660 is a selective PPARβ/δ antagonist. It may down-regulate PPARβ by binding to its ligand-binding domain, preventing the receptor's activation and subsequent gene transcription.

β-Catenin/Tcf Inhibitor, FH535

108409-83-2sc-221398
sc-221398A
10 mg
50 mg
$182.00
$374.00
7
(1)

FH535 is an inhibitor of both PPARγ and PPARδ. It can potentially down-regulate PPARβ by inhibiting its transcriptional activity.

MK-886 sodium salt

118427-55-7sc-200608B
sc-200608
sc-200608A
1 mg
5 mg
25 mg
$47.00
$95.00
$378.00
3
(1)

While MK886 is a FLAP inhibitor, it has been shown to decrease PPAR activity, potentially influencing PPARβ.

Bisphenol A

80-05-7sc-391751
sc-391751A
100 mg
10 g
$300.00
$490.00
5
(0)

Bisphenol A, an environmental endocrine disruptor, can bind PPARs. Its complex interactions might lead to down-regulation of PPARβ in specific contexts.