PPAR beta Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
GW501516 is a potent agonist of the peroxisome proliferator-activated receptor beta (PPARβ), known for its ability to enhance fatty acid oxidation and improve metabolic efficiency. Its unique binding affinity promotes receptor activation, leading to the modulation of genes involved in energy homeostasis. The compound's distinct molecular interactions facilitate the recruitment of coactivators, influencing transcriptional regulation and metabolic pathways, while its kinetic properties allow for sustained receptor engagement. | ||||||
GW 0742 | 317318-84-6 | sc-203991 sc-203991A | 10 mg 50 mg | $194.00 $831.00 | 11 | |
GW 0742 is a selective agonist of the peroxisome proliferator-activated receptor beta (PPARβ), characterized by its high affinity for the receptor's ligand-binding domain. This compound initiates a cascade of molecular events, enhancing the transcription of genes linked to lipid metabolism and energy expenditure. Its unique structural features enable specific interactions with coactivators, promoting a robust transcriptional response. Additionally, GW 0742 exhibits favorable kinetics, ensuring prolonged receptor activation and sustained biological effects. | ||||||
Carbacyclin (Carbocyclic PGI2) | 69552-46-1 | sc-201250 sc-201250A | 1 mg 5 mg | $357.00 $989.00 | 8 | |
Carbacyclin, a carbocyclic derivative of prostacyclin, acts as a PPAR beta agonist, engaging in unique molecular interactions that modulate gene expression related to metabolic processes. Its distinct cyclic structure facilitates specific binding to the receptor, influencing downstream signaling pathways. The compound's reaction kinetics allow for a nuanced regulation of transcriptional activity, enhancing the stability and efficacy of its interactions with nuclear coactivators, thereby fine-tuning metabolic responses. | ||||||
L-165041 | 79558-09-1 | sc-203094 | 5 mg | $156.00 | ||
L-165041 is a selective PPAR beta agonist characterized by its unique ability to engage in specific hydrogen bonding and hydrophobic interactions with the receptor's ligand-binding domain. This compound exhibits a distinct conformational flexibility that enhances its binding affinity, promoting the activation of metabolic gene networks. Its kinetic profile suggests a rapid onset of action, allowing for precise modulation of transcriptional responses, which may influence lipid metabolism and energy homeostasis. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $31.00 $46.00 $122.00 $204.00 | 5 | |
Bezafibrate functions as a PPAR beta agonist, distinguished by its capacity to stabilize receptor conformations through unique electrostatic interactions and van der Waals forces. This compound demonstrates a notable ability to modulate gene expression by influencing chromatin remodeling and recruitment of coactivators. Its reaction kinetics reveal a gradual activation profile, allowing for sustained transcriptional modulation, which may impact cellular energy dynamics and metabolic pathways. | ||||||
2-Bromohexadecanoic acid | 18263-25-7 | sc-251714 sc-251714A | 10 g 50 g | $53.00 $201.00 | 4 | |
2-Bromohexadecanoic acid acts as a PPAR beta agonist, characterized by its ability to form strong hydrogen bonds and hydrophobic interactions with the receptor. This compound uniquely influences lipid metabolism by altering fatty acid oxidation pathways. Its kinetic profile suggests a rapid initial binding followed by a slower dissociation, facilitating prolonged receptor activation. Additionally, it may induce conformational changes that enhance the receptor's affinity for specific DNA response elements, thereby fine-tuning metabolic regulation. | ||||||
CAY10592 | 685139-10-0 | sc-223873 sc-223873A | 1 mg 5 mg | $34.00 $152.00 | ||
CAY10592 functions as a PPAR beta agonist, distinguished by its selective binding affinity and unique allosteric modulation of the receptor. This compound engages in specific electrostatic interactions that stabilize the receptor-ligand complex, promoting enhanced transcriptional activity. Its kinetic behavior indicates a biphasic binding pattern, allowing for both immediate and sustained receptor engagement. Furthermore, CAY10592 may influence downstream signaling pathways, contributing to intricate regulatory networks in cellular metabolism. | ||||||
CAY15073 | 853652-40-1 | sc-364376 sc-364376A | 500 µg 1 mg | $70.00 $98.00 | ||
CAY15073 acts as a PPAR beta agonist, characterized by its unique ability to induce conformational changes in the receptor that enhance its transcriptional efficacy. This compound exhibits a distinctive binding profile, favoring specific hydrophobic interactions that facilitate receptor dimerization. Its reaction kinetics reveal a rapid onset of action, coupled with prolonged receptor activation, which may modulate gene expression involved in lipid metabolism and energy homeostasis. | ||||||