PPAR alpha Activators
Items 1 to 10 of 44 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Directly binds to PPARα to induce its transcriptional activity. | ||||||
LTB4 (Leukotriene B4) | 71160-24-2 | sc-201043 | 50 µg | $367.00 | 4 | |
Leukotriene B4 (LTB4) acts as a potent PPAR alpha modulator, exhibiting specific binding affinities that facilitate unique conformational shifts in the receptor. This compound engages in hydrophobic interactions that enhance its stability within lipid environments, promoting effective signal transduction. LTB4's role in inflammatory pathways is underscored by its rapid kinetics, allowing for swift cellular responses. Its structural features enable diverse interactions with other biomolecules, influencing various physiological processes. | ||||||
(+)-Etomoxir sodium salt | 828934-41-4 | sc-215009 sc-215009A | 5 mg 25 mg | $148.00 $496.00 | 3 | |
(+)-Etomoxir sodium salt functions as a selective PPAR alpha modulator, characterized by its ability to disrupt fatty acid oxidation pathways. It exhibits unique binding dynamics, favoring specific conformations that alter receptor activity. The compound's interactions with lipid membranes enhance its bioavailability, while its kinetic profile allows for sustained engagement with target proteins. This modulation of metabolic pathways highlights its role in energy homeostasis and lipid metabolism. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $65.00 $262.00 | 2 | |
Binds to PPARα, enhancing its activity and lipid metabolism regulation. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $28.00 $37.00 | 18 | |
Indomethacin acts as a PPAR alpha modulator, influencing lipid metabolism through distinct molecular interactions. It engages with the receptor's ligand-binding domain, promoting conformational changes that enhance transcriptional activity. The compound's hydrophobic characteristics facilitate its integration into lipid bilayers, affecting membrane fluidity and receptor accessibility. Its kinetic behavior suggests a prolonged interaction with PPAR alpha, potentially altering gene expression related to fatty acid metabolism and energy regulation. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $133.00 | 7 | |
A synthetic agonist that binds to PPARα to activate it. | ||||||
Palmitoylethanolamide | 544-31-0 | sc-202754 sc-202754A sc-202754B sc-202754C sc-202754D | 10 mg 50 mg 500 mg 1 g 10 g | $78.00 $238.00 $2050.00 $3274.00 $16330.00 | ||
Palmitoylethanolamide functions as a PPAR alpha agonist, engaging in specific interactions that modulate gene expression linked to lipid homeostasis. Its unique structure allows for selective binding within the receptor's hydrophobic pocket, triggering downstream signaling pathways. The compound exhibits a favorable affinity for fatty acid-binding proteins, enhancing its bioavailability and stability. This interaction profile suggests a nuanced role in metabolic regulation, influencing cellular energy dynamics. | ||||||
Clofibric acid | 882-09-7 | sc-203000 sc-203000A | 10 g 50 g | $24.00 $39.00 | 1 | |
Clofibric acid acts as a PPAR alpha agonist, influencing lipid metabolism through its distinct molecular interactions. Its structural conformation enables effective binding to the receptor, facilitating the activation of transcriptional programs that regulate fatty acid oxidation. The compound's ability to alter the expression of genes involved in lipid transport and metabolism highlights its role in modulating energy homeostasis. Additionally, its kinetic properties suggest a rapid onset of action within metabolic pathways. | ||||||
GW 7647 | 265129-71-3 | sc-203068A sc-203068 sc-203068B sc-203068C | 1 mg 5 mg 10 mg 25 mg | $48.00 $167.00 $262.00 $648.00 | 6 | |
A potent PPARα agonist that binds directly to activate the receptor. | ||||||
Muraglitazar | 331741-94-7 | sc-211931 | 1 mg | $326.00 | 1 | |
Muraglitazar functions as a PPAR alpha agonist, engaging in unique molecular interactions that enhance fatty acid catabolism. Its specific binding affinity promotes the recruitment of coactivators, leading to the modulation of gene expression related to lipid metabolism. The compound exhibits distinct reaction kinetics, allowing for a nuanced regulation of metabolic pathways. Furthermore, its structural characteristics facilitate selective activation of downstream signaling cascades, influencing overall metabolic homeostasis. | ||||||