POSH2 Activators
POSH2 activators are chemical compounds that can enhance the functional activity of POSH2 by influencing specific signaling pathways or biological processes that POSH2 is directly involved in. If POSH2 is a protein that is analogous or related to the known POSH (Plenty of SH3s) protein, activators of this protein would be chemicals that modulate its activity. Like activators of the known POSH protein, POSH2 activators function by either directly interacting with the protein to enhance its activity or by indirectly increasing its expression or stability within the cell.
Direct activators bind to specific domains of POSH2, potentially triggering a change in its conformation that could increase its ability to interact with other proteins or its enzymatic activity, depending on the protein's function. For example, if POSH2 were involved in a signaling pathway, direct activators could enhance its ability to assemble signaling complexes or facilitate the transfer of signals by enhancing its interactions with downstream effectors. Indirect activators, on the other hand, could include compounds that increase the transcription of the POSH2 gene, leading to a higher concentration of the protein in the cell, or molecules that inhibit the degradation pathways targeting POSH2, thereby prolonging its cellular lifespan. Indirect activation could also be achieved through the modulation of upstream signaling pathways, which could lead to post-translational modifications of POSH2 that augment its activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an adenylyl cyclase activator that increases the production of cAMP. This can enhance the functional activity of POSH2, which is involved in cAMP-dependent signaling pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-specific inhibitor of phosphodiesterases (PDEs). It increases cAMP levels in cells, enhancing the functional activity of POSH2 in cAMP-dependent signaling pathways. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a specific inhibitor of PDE4. It increases intracellular cAMP by preventing its breakdown, thereby enhancing the functional activity of POSH2 in cAMP-dependent signaling pathways. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates adenylyl cyclase via beta-adrenergic receptors, leading to increased cAMP levels. This can enhance the functional activity of POSH2 in cAMP-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC). PKC phosphorylates and activates POSH2, enhancing its functional activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A. It leads to increased phosphorylation levels of proteins, including POSH2, enhancing its functional activity. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A is a potent inhibitor of protein phosphatases PP1 and PP2A. It can increase the phosphorylation levels of various proteins, including POSH2, enhancing its functional activity. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. It could lead to altered phosphorylation status of POSH2, enhancing its functional activity. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Vanadate is a potent inhibitor of protein tyrosine phosphatases. It can enhance the phosphorylation status of various proteins, including POSH2. | ||||||