Polycystin-1 Inhibitors
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Casein Kinase I Inhibitor, D4476 | 301836-43-1 | sc-202522 | 1 mg | $97.00 | 6 | |
Casein Kinase I Inhibitor, D4476, is a selective inhibitor that modulates signaling pathways by targeting casein kinase I, influencing cellular processes such as circadian rhythms and Wnt signaling. Its unique ability to disrupt protein-protein interactions allows for the alteration of phosphorylation states, impacting downstream effectors. The compound exhibits distinct kinetic properties, facilitating rapid binding and unbinding, which enhances its efficacy in experimental settings. | ||||||
Ro 31-8220 | 138489-18-6 | sc-200619 sc-200619A | 1 mg 5 mg | $90.00 $240.00 | 17 | |
Ro 31-8220 is a potent inhibitor that selectively targets protein kinase C, influencing various cellular signaling pathways. Its unique molecular interactions allow it to modulate phosphorylation events, thereby affecting cellular responses to growth factors and stress. The compound demonstrates distinct reaction kinetics, characterized by a rapid onset of action and a prolonged duration of effect, which can lead to significant alterations in cellular behavior and gene expression profiles. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which is involved in cell growth and proliferation. By doing so, it may downregulate Polycystin-1 expression linked to cell growth. | ||||||
Fasudil, Monohydrochloride Salt | 105628-07-7 | sc-203418 sc-203418A sc-203418B sc-203418C sc-203418D sc-203418E sc-203418F | 10 mg 50 mg 250 mg 1 g 2 g 5 g 10 g | $18.00 $32.00 $85.00 $165.00 $248.00 $486.00 $910.00 | 5 | |
Fasudil, Monohydrochloride Salt, acts as a modulator of Polycystin-1, engaging in specific molecular interactions that influence calcium signaling and cellular mechanotransduction. Its unique ability to stabilize protein conformations enhances the receptor's functionality, promoting effective signal transduction. The compound exhibits distinctive reaction kinetics, facilitating rapid cellular responses while maintaining prolonged engagement with target pathways, ultimately impacting cellular architecture and function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, disrupting the PI3K/Akt/mTOR signaling pathway, which is associated with reduced Polycystin-1 levels. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor, which can impede the signaling pathways leading to Polycystin-1 expression. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Sorafenib targets multiple kinases and inhibits cell proliferation. Its action may indirectly lead to decreased Polycystin-1 expression. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
Sunitinib inhibits receptor tyrosine kinases, potentially downregulating signaling pathways involved in Polycystin-1 expression. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
Erlotinib targets the EGFR pathway, which is implicated in the regulation of Polycystin-1 expression, potentially reducing its levels. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Gefitinib is an EGFR inhibitor, and by blocking EGFR, it may influence signaling pathways that regulate Polycystin-1 expression. | ||||||