Santa Cruz Biotechnology now offers a broad range of PKC Activators. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKC Activators offered by Santa Cruz activate PKC and, in some cases, other cell growth and differentiation related proteins. View detailed PKC Activator specifications, including PKC Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Zoledronic acid monohydrate | 165800-06-6 | sc-202859 sc-202859A sc-202859B | 25 mg 100 mg 1 g | $95.00 $289.00 $658.00 | 5 | |
Zoledronic acid monohydrate exhibits unique properties as a protein kinase C (PKC) modulator by engaging in selective hydrogen bonding with key amino acid residues. This interaction promotes conformational changes that enhance the enzyme's activity. Its structural features facilitate the formation of stable complexes with lipid membranes, influencing the dynamics of PKC translocation and activation. Additionally, its ability to alter ionic interactions within the enzyme's active site contributes to its distinct kinetic profile. | ||||||
12-Deoxyphorbo 13-Angelate 20-Acetate | 25090-72-6 | sc-287294 | 1 mg | $169.00 | ||
12-Deoxyphorbo 13-Angelate 20-Acetate acts as a potent modulator of protein kinase C (PKC) through its unique ability to interact with the enzyme's regulatory domains. This compound induces specific allosteric changes, enhancing PKC's affinity for phospholipid substrates. Its hydrophobic regions promote membrane association, which is crucial for PKC activation. Furthermore, it influences the phosphorylation cascade by modulating the enzyme's interaction with downstream signaling partners, thereby affecting cellular signaling pathways. | ||||||
6-(N-Decylamino)-4-Hydroxymethylindole | 123597-55-7 | sc-291161 sc-291161A | 1 mg 5 mg | $100.00 $500.00 | ||
6-(N-Decylamino)-4-Hydroxymethylindole serves as a selective modulator of protein kinase C (PKC) by engaging in unique hydrogen bonding and hydrophobic interactions with the enzyme's active site. This compound stabilizes the enzyme's conformation, facilitating substrate binding and enhancing catalytic efficiency. Its long alkyl chain promotes membrane localization, which is essential for PKC's functional activation, ultimately influencing various intracellular signaling cascades. | ||||||
4α-Phorbol 12,13-dibutyrate | 93781-54-5 | sc-352029 | 1 mg | $218.00 | 1 | |
4α-Phorbol 12,13-dibutyrate acts as a potent activator of protein kinase C (PKC) through its ability to mimic diacylglycerol, engaging in specific lipid interactions that promote PKC translocation to the membrane. This compound enhances the enzyme's phosphorylation activity by stabilizing its active conformation, thereby influencing downstream signaling pathways. Its unique structural features allow for selective engagement with various PKC isoforms, modulating cellular responses effectively. | ||||||
Zoledronic Acid, Disodium Salt, Tetrahydrate | 165800-07-7 | sc-208497 sc-208497A sc-208497B | 50 mg 100 mg 250 mg | $219.00 $469.00 $979.00 | ||
Zoledronic Acid, Disodium Salt, Tetrahydrate exhibits unique interactions with cellular signaling pathways by acting as a competitive inhibitor of farnesyl pyrophosphate synthase. This compound disrupts the mevalonate pathway, leading to altered prenylation of proteins, which affects cellular processes such as apoptosis and proliferation. Its tetrahydrate form enhances solubility, facilitating its interaction with target enzymes and influencing reaction kinetics in biochemical assays. | ||||||
Arachidonic Acid methyl ester | 2566-89-4 | sc-362322 | 50 mg | $85.00 | ||
Arachidonic Acid methyl ester serves as a potent modulator of protein kinase C (PKC) activity, engaging in specific lipid-mediated signaling pathways. Its unique structure allows for selective binding to PKC isoforms, influencing downstream phosphorylation events. This compound can alter membrane fluidity, enhancing enzyme accessibility and promoting rapid signal transduction. Additionally, its esterified form may exhibit distinct reactivity in lipid peroxidation processes, impacting cellular responses to oxidative stress. | ||||||
Arachidonic Acid-d8 | 69254-37-1 | sc-205209 sc-205209A | 1 mg 5 mg | $233.00 $801.00 | 5 | |
Arachidonic Acid-d8 serves as a potent modulator of protein kinase C (PKC) activity, distinguished by its deuterated structure that alters its metabolic stability and isotopic labeling. This fatty acid engages in specific interactions with PKC, promoting its activation through unique conformational shifts. Additionally, Arachidonic Acid-d8 participates in lipid signaling pathways, influencing downstream effects on cellular processes and membrane fluidity, thereby impacting various signaling networks. | ||||||
Phorbol | 17673-25-5 | sc-253267 | 5 mg | $270.00 | 1 | |
Phorbol is a highly effective activator of protein kinase C (PKC), characterized by its ability to mimic diacylglycerol, a natural PKC cofactor. Its unique tetracyclic structure facilitates strong interactions with the regulatory domain of PKC, leading to conformational changes that enhance enzyme activity. This compound can also induce translocation of PKC to cellular membranes, amplifying signaling cascades. Furthermore, Phorbol's reactivity with cellular lipids can influence membrane dynamics and protein interactions, shaping various cellular responses. | ||||||
8-MA-cAMP | 33823-18-6 | sc-257017 | 5 mg | $200.00 | ||
8-MA-cAMP is a selective modulator of protein kinase C (PKC) that enhances its activity through unique allosteric interactions. This compound stabilizes specific conformations of PKC, facilitating its phosphorylation of target substrates. Its kinetic profile reveals a rapid onset of action, influencing intracellular signaling cascades. Additionally, 8-MA-cAMP's structural features allow for distinct binding affinities, impacting cellular responses and regulatory mechanisms within lipid environments. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
Zoledronic acid, anhydrous, exhibits unique interactions with protein kinase C (PKC) by altering its conformational dynamics. This compound engages in specific hydrogen bonding and hydrophobic interactions, modulating PKC's activity through distinct allosteric sites. Its reaction kinetics demonstrate a notable influence on substrate affinity, enhancing the enzyme's phosphorylation efficiency. Furthermore, the compound's structural characteristics contribute to its selective binding, impacting downstream signaling pathways and cellular regulatory processes. |