Arachidonic Acid-d8 (CAS 69254-37-1)

Arachidonic Acid-d8, with the CAS number 69254-37-1, is a deuterium-labeled analog of arachidonic acid, a polyunsaturated omega-6 fatty acid crucial for the biosynthesis of eicosanoids. This isotopically labeled version of arachidonic acid incorporates deuterium atoms at specific positions, which makes it heavier than its non-labeled counterpart. This unique modification is highly valuable in research, particularly in the study of lipid metabolism and the complex pathways of eicosanoid synthesis through mass spectrometry-based techniques. By substituting hydrogen atoms with deuterium, Arachidonic Acid-d8 provides a stable, non-radioactive tracer that can be distinguished from endogenous arachidonic acid in metabolic studies, allowing researchers to track its incorporation into cellular lipids and the subsequent formation of various metabolites. This capability is critical for elucidating the complex mechanisms by which arachidonic acid is converted into various bioactive molecules like prostaglandins, leukotrienes, and thromboxanes. Utilizing Arachidonic Acid-d8, scientists can achieve more accurate and detailed insights into the dynamics of lipid signaling molecules, enhancing our understanding of cellular processes in various biological contexts, including but not limited to inflammation and cell signaling networks. This research is fundamental in fields such as biochemistry and cellular biology, providing deeper insights into the roles lipids play in cellular functions.