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Arachidonic Acid methyl ester (CAS 2566-89-4)

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Alternate Names:
Methyl Arachidonate
Application:
Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade
CAS Number:
2566-89-4
Molecular Weight:
318.49
Molecular Formula:
C21H34O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. Arachidonic Acid methyl ester is an activator of PKC.


Arachidonic Acid methyl ester (CAS 2566-89-4) References

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  2. Transfomration of arachidonic acid into 12-hydroxy-5,8,10,14-eicosatetraenoic acid by mouse peritoneal macrophages.  |  Rigaud, M., et al. 1979. Biochim Biophys Acta. 573: 408-12. PMID: 109127
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  5. Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids.  |  Zheng, CJ., et al. 2005. FEBS Lett. 579: 5157-62. PMID: 16146629
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  7. Data of added-value lipid production, Arachidonic acid, among other lipids by Mortierella elongata, using low cost simulated wastewater.  |  Fernandes, BS., et al. 2017. Data Brief. 14: 255-259. PMID: 28861449
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  11. Characteristics and specificity of the inhibition of liver glucose-6-phosphatase by arachidonic acid. Lesser inhibitability of the enzyme of diabetic rats.  |  Mithieux, G., et al. 1993. Eur J Biochem. 213: 461-6. PMID: 8386629
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Arachidonic Acid methyl ester, 50 mg

sc-362322
50 mg
$85.00