Date published: 2025-9-10

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PHRF1 Activators

PHRF1 Activators represent a unique class of chemical compounds tailored to enhance or stimulate the function or expression of the protein PHRF1. These activators, stemming from both organic and inorganic realms, are characterized by their high specificity, targeting the PHRF1 protein and its associated pathways without significantly interfering with other unrelated cellular processes. Their modes of action can be multifold, including direct interaction with the PHRF1 protein or indirectly by modulating the broader cellular environment in which PHRF1 operates. Given the intricate nature of cellular signaling, the specificity offered by these activators presents a major advancement in the modulation of protein functions.

The complexity and diversity within the PHRF1 Activators class can be attributed to the multifaceted roles PHRF1 might play in cellular processes. Some activators in this class could be allosteric modulators, binding to sites on the PHRF1 protein distinct from the active or primary binding site, leading to conformational changes that bolster its activity. Others might function by enhancing the stability of PHRF1, ensuring its longer presence and increased action duration within the cellular milieu. Additionally, some activators could work by bolstering the transcription or translation of the PHRF1 gene, ensuring a higher protein yield in the cell. The diversity in mechanisms provides researchers with a wide array of tools to study and understand the nuanced functions and importance of PHRF1 in cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Calcium

7440-70-2sc-252536
5 g
$209.00
(0)

Calcium ions bind to calcium-dependent proteins, triggering conformational changes and facilitating their activation, including proteins associated with PHRF1.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin elevates intracellular cAMP levels, which in turn activate protein kinase A (PKA), leading to the phosphorylation and subsequent activation of PHRF1.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates protein kinase C (PKC), which can phosphorylate and activate PHRF1 through downstream signaling cascades.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc ions serve as cofactors for various enzymes, potentially influencing the activity of proteins involved in PHRF1 activation.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$114.00
$175.00
$260.00
$362.00
$617.00
$1127.00
(1)

cAMP acts as a secondary messenger, activating protein kinase A (PKA), which can phosphorylate and activate PHRF1.

Hydrogen Peroxide

7722-84-1sc-203336
sc-203336A
sc-203336B
100 ml
500 ml
3.8 L
$30.00
$60.00
$93.00
27
(1)

Hydrogen peroxide functions as a reactive oxygen species that can modulate the activity of redox-sensitive proteins and cellular signaling pathways, potentially influencing PHRF1 activation.

Potassium

7440-09-7sc-253297
1 g
$122.00
(0)

Potassium ions participate in maintaining cellular ion balance and may indirectly influence the activity of ion-sensitive proteins involved in PHRF1 activation.

Sodium Orthovanadate

13721-39-6sc-3540
sc-3540B
sc-3540A
5 g
10 g
50 g
$45.00
$56.00
$183.00
142
(4)

Sodium orthovanadate inhibits phosphatases, leading to enhanced phosphorylation and activation of certain proteins, potentially including PHRF1.

Ionomycin, free acid

56092-81-0sc-263405
sc-263405A
1 mg
5 mg
$94.00
$259.00
2
(2)

Ionomycin increases intracellular calcium concentrations, which can activate calcium-dependent proteins, potentially including those involved in PHRF1 activation.