PHRF1 Activators represent a unique class of chemical compounds tailored to enhance or stimulate the function or expression of the protein PHRF1. These activators, stemming from both organic and inorganic realms, are characterized by their high specificity, targeting the PHRF1 protein and its associated pathways without significantly interfering with other unrelated cellular processes. Their modes of action can be multifold, including direct interaction with the PHRF1 protein or indirectly by modulating the broader cellular environment in which PHRF1 operates. Given the intricate nature of cellular signaling, the specificity offered by these activators presents a major advancement in the modulation of protein functions.
The complexity and diversity within the PHRF1 Activators class can be attributed to the multifaceted roles PHRF1 might play in cellular processes. Some activators in this class could be allosteric modulators, binding to sites on the PHRF1 protein distinct from the active or primary binding site, leading to conformational changes that bolster its activity. Others might function by enhancing the stability of PHRF1, ensuring its longer presence and increased action duration within the cellular milieu. Additionally, some activators could work by bolstering the transcription or translation of the PHRF1 gene, ensuring a higher protein yield in the cell. The diversity in mechanisms provides researchers with a wide array of tools to study and understand the nuanced functions and importance of PHRF1 in cellular biology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Calcium ions bind to calcium-dependent proteins, triggering conformational changes and facilitating their activation, including proteins associated with PHRF1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin elevates intracellular cAMP levels, which in turn activate protein kinase A (PKA), leading to the phosphorylation and subsequent activation of PHRF1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate and activate PHRF1 through downstream signaling cascades. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc ions serve as cofactors for various enzymes, potentially influencing the activity of proteins involved in PHRF1 activation. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
cAMP acts as a secondary messenger, activating protein kinase A (PKA), which can phosphorylate and activate PHRF1. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Hydrogen peroxide functions as a reactive oxygen species that can modulate the activity of redox-sensitive proteins and cellular signaling pathways, potentially influencing PHRF1 activation. | ||||||
Potassium | 7440-09-7 | sc-253297 | 1 g | $122.00 | ||
Potassium ions participate in maintaining cellular ion balance and may indirectly influence the activity of ion-sensitive proteins involved in PHRF1 activation. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium orthovanadate inhibits phosphatases, leading to enhanced phosphorylation and activation of certain proteins, potentially including PHRF1. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin increases intracellular calcium concentrations, which can activate calcium-dependent proteins, potentially including those involved in PHRF1 activation. |