Phospholipase A2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quinacrine Dihydrochloride Dihydrate | 6151-30-0 | sc-391946B sc-391946C sc-391946 sc-391946A | 1 g 5 g 10 g 25 g | $42.00 $84.00 $161.00 $338.00 | 1 | |
Quinacrine Dihydrochloride Dihydrate acts as a phospholipase A2 inhibitor, modulating lipid metabolism by interfering with the hydrolysis of phospholipids. Its unique binding affinity to the enzyme alters the catalytic activity, impacting the release of arachidonic acid. The compound exhibits distinct solubility properties, enhancing its interaction with membrane structures. Additionally, its ability to form hydrogen bonds may influence enzyme conformation, affecting reaction kinetics and substrate accessibility. | ||||||
Polydatin | 65914-17-2 | sc-203203 | 10 mg | $92.00 | 5 | |
Polydatin functions as a phospholipase A2 modulator, influencing lipid signaling pathways through its interaction with membrane phospholipids. Its structural characteristics allow for specific binding to the enzyme, potentially altering substrate affinity and catalytic efficiency. The compound's hydrophilic and lipophilic balance enhances its integration into lipid bilayers, affecting membrane fluidity. Furthermore, Polydatin's capacity to stabilize enzyme conformations may lead to altered reaction kinetics, impacting downstream signaling events. | ||||||
FKGK 11 | 1071000-98-0 | sc-223989 sc-223989A | 500 µg 1 mg | $54.00 $136.00 | ||
FKGK 11 acts as a phospholipase A2 by selectively interacting with lipid membranes, facilitating the hydrolysis of phospholipids. Its unique structural motifs enable it to preferentially bind to specific lipid substrates, modulating enzyme activity and influencing lipid-derived signaling cascades. The compound exhibits distinct reaction kinetics, characterized by a rapid turnover rate, which may enhance its efficacy in lipid metabolism. Additionally, FKGK 11's amphipathic nature promotes its localization within membrane domains, potentially affecting membrane organization and dynamics. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin functions as a phospholipase A2 by engaging in specific interactions with membrane phospholipids, leading to the cleavage of fatty acid chains. Its flavonoid structure allows for unique binding affinities, influencing the enzyme's substrate specificity and catalytic efficiency. The compound's ability to alter membrane fluidity and composition can impact cellular signaling pathways, while its antioxidant properties may modulate oxidative stress responses in lipid environments. | ||||||
Nidulin | 10089-10-8 | sc-202244 | 1 mg | $400.00 | ||
Nidulin acts as a phospholipase A2 by selectively hydrolyzing phospholipid substrates, facilitating the release of arachidonic acid. Its unique structural features enable it to stabilize transition states during catalysis, enhancing reaction kinetics. The compound's interactions with lipid bilayers can induce conformational changes, affecting membrane integrity and permeability. Additionally, Nidulin's role in modulating lipid signaling pathways highlights its influence on cellular responses to environmental stimuli. | ||||||
ONO-RS-082 | 99754-06-0 | sc-201410 sc-201410A | 20 mg 100 mg | $81.00 $225.00 | ||
ONO-RS-082 functions as a phospholipase A2 by engaging in the hydrolysis of phospholipids, leading to the liberation of fatty acids. Its distinct binding affinity for specific lipid substrates allows for precise modulation of membrane dynamics. The compound exhibits unique catalytic efficiency, influenced by its ability to form stable enzyme-substrate complexes. Furthermore, ONO-RS-082's interactions with cellular membranes can alter lipid raft composition, impacting signal transduction pathways. | ||||||