Quinacrine Dihydrochloride Dihydrate CAS: 6151-30-0
MF: C23H30ClN3O•2HCl•2H20
MW: 508.92
A phophoslipase A2 inhibitor.

Quinacrine Dihydrochloride Dihydrate (CAS 6151-30-0)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 114ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: Atabrine hydrochloride; RP-866; SN-390
Application: Quinacrine Dihydrochloride Dihydrate is a phophoslipase A2 inhibitor
CAS Number: 6151-30-0
Molecular Weight: 508.92
Molecular Formula: C23H30ClN3O•2HCl•2H20
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Quinacrine Dihydrochloride Dihydrate is a PLA2 (phophoslipase A2) inhibitor. It shows synergistic inhibition of prostate cancer cells when used in combination with paclitaxel or lovastatin. Quinacrine Dihydrochloride Dihydrate is an inhibitor of AChR, cPLA2, MAO-A and MAO-B.

Physical State :
Solid
Solubility :
Soluble in hot water, ethanol (slightly), and methanol (slightly). Insoluble in ether, and acetone.
Storage :
Store at room temperature
Melting Point :
248-250° C (dec.)
Refractive Index :
n20D ~1.62 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 0.08 nM; Human immunodeficiency virus 1: IC50 = 2.15 µM; Voltage-dependent sodium channels: IC50 = 3.3 µM; Aldehyde oxidase: IC50 = 3.3 µM; Phospholipase A2: IC50 = 17 µM (porcine pancreas)
Ki Data :
Riboflavin-binding protein: Ki= 6.7 µM
Fluoresence :
λex 417 nm, λem 496 nm in 30 mM Tris; 0.2 M sucrose
pK Values :
pKa1 = 9.4; pKa2 = 10.7 (amines) (est)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
2725002
Merck Index :
14: 8044
MDL Number :
MFCD00150069
SMILES :
CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC.O.O.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 137ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.