Date published: 2026-5-7

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PGAM1 Activators

The class of chemicals termed PGAM1 Activators is not well-defined. However, considering the biological role of PGAM1, molecules involved in the glycolytic pathway indirectly influence its activity. Glucose, the starting molecule of glycolysis, initiates the pathway that involves PGAM1. Insulin, a hormone that promotes glucose uptake and utilization, indirectly influences the glycolytic pathway and thus PGAM1. Fructose-1,6-bisphosphate, an intermediate in glycolysis, is an upstream molecule that can indirectly influence PGAM1.

2,3-Bisphosphoglycerate, a metabolite in the glycolytic pathway, is known to activate the muscle-specific isozyme of PGAM1. Lastly, pyruvate, the end product of glycolysis, might influence PGAM1 activity through feedback mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D(+)Glucose, Anhydrous

50-99-7sc-211203
sc-211203B
sc-211203A
250 g
5 kg
1 kg
$38.00
$198.00
$65.00
5
(1)

Glucose initiates the glycolytic pathway, which involves PGAM1.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin promotes glucose uptake and utilization, indirectly influencing the glycolytic pathway and PGAM1.

D-Fructose 1,6-bisphosphate sodium salt

488-69-7sc-484714
50 g
$304.00
(0)

Fructose-1,6-bisphosphate is an upstream molecule in the glycolytic pathway and thus indirectly influences PGAM1.

Pyruvic acid

127-17-3sc-208191
sc-208191A
25 g
100 g
$41.00
$96.00
(0)

Pyruvate, the end product of glycolysis, might influence PGAM1 activity through feedback mechanisms.