Peroxin 2 Activators belong to a distinct chemical class that plays a pivotal role in cellular processes associated with peroxisomes, membrane-bound organelles essential for various metabolic functions. Peroxisomes are involved in lipid metabolism, detoxification reactions, and the breakdown of hydrogen peroxide. Peroxin 2, also known as PEX2, is a critical component of the peroxisomal protein import machinery, facilitating the translocation of newly synthesized proteins into peroxisomes. Peroxin 2 Activators are characterized by their ability to modulate the activity of PEX2, thereby influencing the efficiency of peroxisomal protein import and subsequent peroxisome function.
The activation of Peroxin 2 is integral for maintaining cellular homeostasis, as peroxisomes contribute to lipid metabolism, the catabolism of long-chain fatty acids, and the synthesis of plasmalogens. These processes are essential for cellular energy production and membrane integrity. Peroxin 2 Activators are thought to enhance the functionality of peroxisomes by promoting the proper localization and assembly of peroxisomal proteins. The intricate regulation of peroxisomal functions mediated by Peroxin 2 Activators underscores their significance in cellular metabolism and highlights the complexity of cellular organelle dynamics. Further elucidating the molecular mechanisms underlying the activation of Peroxin 2 may provide valuable insights into cellular processes related to peroxisomes and may have implications for understanding metabolic disorders associated with peroxisomal dysfunction.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Cholic acid | 81-25-4 | sc-255020 sc-255020A sc-255020B sc-255020C sc-255020D | 25 g 100 g 500 g 1 kg 5 kg | $48.00 $121.00 $567.00 $998.00 $4480.00 | 11 | |
Cholic Acid is a major primary bile acid produced in the liver. It impacts the translocation of proteins to the peroxisomes, a process in which Peroxin 2 is directly involved. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid. DHA is involved in the modulation of peroxisomal beta-oxidation, a process in which Peroxin 2 is involved. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $36.00 $102.00 $569.00 $1173.00 | 10 | |
Oleic Acid is a common monounsaturated fat in human diet. It enhances Peroxin 2 by promoting the biogenesis of peroxisomes, a key function of Peroxin 2. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynasore is a potent inhibitor of dynamin, impacting the endocytic pathway. Dynasore can increase Peroxin 2 activity by influencing peroxisome proliferation. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone is a thiazolidinedione drug which activates the peroxisome proliferator-activated receptor gamma (PPAR-gamma). This activation leads to the enhanced function of Peroxin 2, as PPAR-gamma is involved in the regulation of peroxisome proliferation. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate is used to reduce cholesterol levels. It activates Peroxisome Proliferator-Activated Receptor (PPAR), leading to increased peroxisome proliferation, thus enhancing the function of Peroxin 2. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate is a fibric acid derivative. It activates Peroxisome Proliferator-Activated Receptor (PPAR), which leads to increased peroxisome proliferation and consequently enhancing Peroxin 2 function. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid is a metabolite of Vitamin A. It influences the biogenesis of peroxisomes, a process that Peroxin 2 is involved in, thus enhancing its function. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $96.00 $334.00 | 50 | |
Lysophosphatidic Acid is a bioactive phospholipid. It enhances the functionality of Peroxin 2 by boosting peroxisome proliferation, which is a key function of Peroxin 2. |