P42pop activators are a set of chemicals that can indirectly influence the activity of the protein MYPOP. Central to this is the modulation of signaling pathways and cellular processes that are potentially associated with MYPOP. For instance, agents like Forskolin and 8-Bromo-cAMP elevate cAMP levels, subsequently activating protein kinase A (PKA). Another avenue of modulation comes from agents that target the PI3K/AKT and ERK pathways, like EGF and LY294002. These compounds influence the cascades of protein interactions and phosphorylation events that can reach and modulate various proteins, including those less characterized like MYPOP.
Likewise, agents such as IBMX and Okadaic Acid can alter the cellular landscape by modulating cAMP levels and protein phosphatases, respectively. In both instances, the resultant changes in cellular signaling and protein activities can have ramifications on proteins linked to these pathways. The same principle applies to compounds that act on mTOR, JNK, p38 MAPK, and AMPK pathways, such as Rapamycin, Anisomycin, and AICAR.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cyclic AMP levels. Elevated cAMP can activate protein kinase A (PKA) which may, in turn, modulate proteins like MYPOP. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
A cAMP analog that can activate PKA, potentially influencing MYPOP by modulating associated signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This is a PI3K inhibitor. By modulating the PI3K/AKT pathway, it can influence proteins that are regulated by this pathway, including potentially MYPOP. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX inhibits phosphodiesterase, leading to increased cAMP levels. Elevated cAMP levels can activate PKA and thereby potentially influence MYPOP. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic Acid inhibits protein phosphatases PP1 and PP2A, potentially modulating pathways that may indirectly influence MYPOP. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 inhibits MEK, influencing the ERK signaling pathway. If MYPOP is linked with this pathway, its activity can be modulated indirectly. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which affects several signaling pathways. Indirect activation of MYPOP can occur if it has intersections with mTOR-modulated pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin activates JNK and p38 MAPK pathways, which can indirectly modulate MYPOP if it is associated with these signaling cascades. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates Protein Kinase C (PKC), which modulates various signaling pathways. Indirect activation of MYPOP can be influenced by these PKC-mediated pathways. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMP-activated protein kinase (AMPK). By modulating this pathway, it can indirectly influence proteins including potentially MYPOP. | ||||||