OTTMUSG00000004551 Activators
C8orf88, also known as Gene model 11837 (Gm11837), represents a protein with a growing significance in cellular processes, although its precise function is still the subject of ongoing research. The activation of C8orf88 is intricately tied to the modulation of cyclic AMP (cAMP) signaling pathways, highlighting its potential role as a key regulator within the cellular milieu. Activation of C8orf88 is predominantly mediated through the regulation of intracellular cAMP levels. Chemical activators such as forskolin, isoproterenol, IBMX, caffeine, epinephrine, rolipram, NKH477, prostaglandin E2 (PGE2), terbutaline, theophylline, and clenbuterol play crucial roles in modulating cAMP signaling pathways. These activators either directly stimulate adenylate cyclase or inhibit phosphodiesterases, ultimately leading to an increase in cAMP levels. This elevation in cAMP levels, in turn, triggers the activation of C8orf88 via downstream signaling cascades.
In conclusion, C8orf88, while still in the process of being fully elucidated in terms of its function, exhibits close ties to the regulation of cAMP signaling within the cell. Chemical activators act as pivotal regulators in these pathways, potentially influencing the activity of C8orf88 and its role in cellular processes. Further research is essential to decipher the specific functions and implications of C8orf88 activation in the context of cellular physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates C8orf88 through beta-adrenergic receptor stimulation, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX activates C8orf88 by inhibiting phosphodiesterases, resulting in elevated cAMP levels, which activate the protein via downstream signaling pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine activates C8orf88 by antagonizing adenosine receptors, leading to increased cAMP production and subsequent functional activation of the protein. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates C8orf88 by binding to beta-adrenergic receptors, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram activates C8orf88 by selectively inhibiting phosphodiesterase 4, increasing cAMP levels, and subsequently activating the protein. | ||||||
Cilomilast | 153259-65-5 | sc-483188 | 5 mg | $132.00 | 1 | |
NKH477 activates C8orf88 by inhibiting phosphodiesterase 3, leading to an increase in cAMP levels, which results in the functional activation of the protein. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates C8orf88 through its receptor EP2, triggering adenylate cyclase activity, cAMP elevation, and protein activation via downstream signaling pathways. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline activates C8orf88 by inhibiting phosphodiesterases, increasing cAMP levels, and leading to the functional activation of the protein. | ||||||
Salbutamol | 18559-94-9 | sc-253527 sc-253527A | 25 mg 50 mg | $94.00 $141.00 | ||
Salbutamol activates C8orf88 by binding to beta-adrenergic receptors, stimulating adenylate cyclase, increasing cAMP levels, and subsequently activating the protein. | ||||||