OTTMUSG00000003605 Activators
CD300 molecule-like family member D4 isoform X6, encoded by the Cd300ld4 gene, plays a significant role in immune responses and cellular signaling. This protein is associated with the regulation of immune cell activation and inflammation. Activation of CD300 molecule-like family member D4 isoform X6 is achieved through various mechanisms, involving the interaction with specific ligands and modulation of intracellular signaling pathways. The activation of CD300 molecule-like family member D4 isoform X6 can be initiated by different chemical activators. Phorbol 12-myristate 13-acetate (PMA) stimulates protein kinase C (PKC), which in turn activates the protein through downstream signaling cascades. Ionomycin induces calcium influx, triggering PKC activation and subsequent functional activation. Lipopolysaccharide (LPS) indirectly activates the protein by promoting Toll-like receptor (TLR) signaling. Interferon-gamma (IFN-γ) activates CD300 molecule-like family member D4 isoform X6 through JAK-STAT signaling, leading to increased expression and functional activation.
Additionally, molecules like phosphatidylserine (PS), thapsigargin, and PIP2 (Phosphatidylinositol 4,5-bisphosphate) directly interact with CD300 molecule-like family member D4 isoform X6, initiating intracellular signaling events and functional activation. R-Phycoerythrin (R-PE) activates the protein through specific binding, while Pam3CSK4 indirectly engages TLR2 to trigger downstream signaling and protein activation. 2-Deoxy-D-glucose (2-DG) disrupts glycolysis, leading to metabolic changes and functional activation, while wortmannin inhibits PI3-kinase, disrupting downstream signaling. Staurosporine activates CD300 molecule-like family member D4 isoform X6 by inhibiting various kinases, leading to unregulated signaling and functional activation. In summary, CD300 molecule-like family member D4 isoform X6 plays a crucial role in immune responses and cellular signaling. Its activation is achieved through various chemical activators that modulate intracellular pathways, contributing to immune cell regulation and inflammation control. These activators, by engaging specific mechanisms, ensure the proper functioning of CD300 molecule-like family member D4 isoform X6 in the context of immune system regulation and cellular responses to external stimuli.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates CD300 molecule-like family member D4 isoform X6 by stimulating protein kinase C (PKC) and subsequent downstream signaling, leading to its functional activation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin activates CD300 molecule-like family member D4 isoform X6 by inducing calcium influx, which triggers PKC activation and subsequent protein activation. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS activates CD300 molecule-like family member D4 isoform X6 indirectly by promoting Toll-like receptor (TLR) signaling and downstream activation of the protein. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin activates CD300 molecule-like family member D4 isoform X6 by depleting intracellular calcium stores, triggering PKC activation and protein activation. | ||||||
R-Phycoerythrin | 11016-17-4 | sc-359902 sc-359902A | 5 mg 100 mg | $275.00 $1155.00 | 2 | |
R-PE activates CD300 molecule-like family member D4 isoform X6 through specific binding, initiating intracellular signaling cascades and functional activation. | ||||||
Pam3Cys-Ser-(Lys)4, Hydrochloride | 112208-00-1 | sc-507471 | 2 mg | $550.00 | ||
Pam3CSK4 activates CD300 molecule-like family member D4 isoform X6 indirectly by engaging TLR2 and triggering downstream signaling, resulting in protein activation. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-DG activates CD300 molecule-like family member D4 isoform X6 by inhibiting glycolysis, leading to metabolic changes and subsequent functional activation of the protein. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin activates CD300 molecule-like family member D4 isoform X6 by inhibiting PI3-kinase, which disrupts downstream signaling and functional activation of the protein. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine activates CD300 molecule-like family member D4 isoform X6 by inhibiting various kinases, leading to unregulated signaling and functional activation of the protein. | ||||||