Date published: 2025-11-1

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OR8U1 Inhibitors

OR8U1 inhibitors represent a distinct chemical class designed to modulate the activity of the OR8U1 receptor. The OR8U1 receptor belongs to the large family of olfactory receptors, which are primarily expressed in the sensory neurons of the olfactory epithelium. These receptors play a pivotal role in detecting and transducing olfactory signals, thereby initiating the perception of various odors. Specifically, OR8U1 is a member of the olfactory receptor gene family, and its inhibition is directed towards regulating the olfactory response associated with this particular receptor. The mechanism of action of OR8U1 inhibitors involves interference with the binding of odor molecules to the OR8U1 receptor. By disrupting the normal activation process, these inhibitors can modulate olfactory signaling pathways, influencing the overall perception of specific odors. Understanding the function of OR8U1 and the impact of its inhibition provides valuable insights into the intricate molecular processes underlying olfaction. Researchers employing OR8U1 inhibitors aim to unravel the complexities of odor recognition and discrimination, shedding light on the precise mechanisms that govern the sense of smell. Such inhibitors serve as essential tools in experimental settings, allowing scientists to explore the nuances of olfactory receptor function and contributing to a deeper understanding of sensory perception.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting RNA polymerase and preventing RNA synthesis, which could reduce OR8U1 mRNA levels and protein expression.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

This toxin from the Amanita mushroom inhibits RNA polymerase II, which is responsible for mRNA synthesis, potentially decreasing OR8U1 expression.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

Rifampicin binds to the beta subunit of RNA polymerase, inhibiting RNA synthesis and potentially reducing the expression of genes like OR8U1.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide has been shown to inhibit the transcription of various genes by affecting RNA polymerase II activity, which could reduce OR8U1 expression.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

DRB is an adenosine analogue that inhibits RNA synthesis by targeting RNA polymerase II, potentially reducing OR8U1 mRNA and protein levels.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

Cordycepin, a derivative of adenosine, inhibits RNA polymerase, which would decrease overall mRNA production, possibly affecting OR8U1 expression.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$169.00
$299.00
66
(3)

Tunicamycin blocks N-linked glycosylation in the ER, leading to ER stress, which can downregulate protein expression, including OR8U1.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step in protein elongation, which could reduce OR8U1 protein levels.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Anisomycin inhibits peptidyl transferase activity in eukaryotic ribosomes, impairing protein synthesis and potentially decreasing OR8U1 expression.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

Puromycin causes premature chain termination during translation, potentially lowering the expression of many proteins including OR8U1.