OR4D5 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quinidine | 56-54-2 | sc-212614 | 10 g | $102.00 | 3 | |
As a known blocker of voltage-gated sodium channels, quinidine can inhibit action potentials in olfactory sensory neurons. Inhibition of these action potentials would prevent the initiation of the signaling cascade that OR4D5 relies on to translate a chemical stimulus into an electrical response. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
This compound is an inhibitor of many calcium channels and can interfere with the calcium-mediated signaling that is essential for the function of OR4D5 in olfactory transduction. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $50.00 $128.00 | ||
Lidocaine is a sodium channel blocker that can inhibit neuronal conduction. By inhibiting these channels in olfactory neurons, lidocaine can reduce the functional activity of OR4D5 by preventing signal propagation. | ||||||
Hexamethonium bromide | 55-97-0 | sc-205712 sc-205712A | 10 g 25 g | $45.00 $63.00 | ||
As a nicotinic receptor antagonist, hexamethonium can inhibit cholinergic neurotransmission. While not directly linked to OR4D5, it can affect the overall neuronal excitability, which could indirectly reduce the functional activity of OR4D5 in olfactory processing. | ||||||
(+)-Bicuculline | 485-49-4 | sc-202498 sc-202498A | 50 mg 250 mg | $80.00 $275.00 | ||
Bicuculline, as a GABA_A receptor antagonist, can increase neuronal excitability. However, in excessive amounts, it can inhibit neuronal activity through overstimulation and desensitization, which could in turn reduce the activity of OR4D5. | ||||||
Cobalt(II) chloride | 7646-79-9 | sc-252623 sc-252623A | 5 g 100 g | $63.00 $173.00 | 7 | |
Cobalt(II) chloride can block calcium channels and, by doing so, it inhibits the calcium influx necessary for the activation of olfactory signal transduction pathways involving OR4D5. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese ions can enter cells through calcium channels and subsequently inhibit them. This inhibition can disrupt calcium signaling in olfactory sensory neurons, potentially reducing OR4D5 activity. | ||||||
Amlodipine | 88150-42-9 | sc-200195 sc-200195A | 100 mg 1 g | $73.00 $163.00 | 2 | |
A known calcium channel blocker, amlodipine can inhibit the influx of calcium that would otherwise trigger the signaling cascade in olfactory neurons where OR4D5 is active. | ||||||
Carbenoxolone | 5697-56-3 | sc-507294 | 1 g | $50.00 | ||
Carbenoxolone is a gap junction inhibitor that can disrupt intercellular communication. In olfactory neurons, this disruption could impede the coordinated activity required for OR4D5 signaling. | ||||||