Molecular structure of Carbenoxolone, CAS Number: 5697-56-3
Carbenoxolone (CAS 5697-56-3)
Alternate Names:
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-(3-carboxypropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
CAS Number:
5697-56-3
Molecular Weight:
570.76
Molecular Formula:
C34H50O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Carbenoxolone (CAS 5697-56-3) References
- Carbenoxolone blocks the light-evoked rise in intracellular calcium in isolated melanopsin ganglion cell photoreceptors. | Bramley, JR., et al. 2011. PLoS One. 6: e22721. PMID: 21829491
- Carbenoxolone Reverses the Amyloid Beta 1-42 Oligomer-Induced Oxidative Damage and Anxiety-Related Behavior in Rats. | Sharma, S., et al. 2019. Neurotox Res. 35: 654-667. PMID: 30402773
- Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line. | Haga, IR., et al. 2018. Sci Rep. 8: 16956. PMID: 30446704
- The Effects of Carbenoxolone against Experimental Autoimmune Encephalomyelitis in a Mouse Model. | Chen, Y., et al. 2020. Neuroimmunomodulation. 27: 19-27. PMID: 32062665
- Inhibiting pannexin-1 alleviates sepsis-induced acute kidney injury via decreasing NLRP3 inflammasome activation and cell apoptosis. | Huang, G., et al. 2020. Life Sci. 254: 117791. PMID: 32416166
- Carbenoxolone and 18β-glycyrrhetinic acid inhibit inositol 1,4,5-trisphosphate-mediated endothelial cell calcium signalling and depolarise mitochondria. | Buckley, C., et al. 2021. Br J Pharmacol. 178: 896-912. PMID: 33269468
- Neuroprotective effects of carbenoxolone against amyloid-beta 1-42 oligomer-induced neuroinflammation and cognitive decline in rats. | Sharma, S., et al. 2021. Neurotoxicology. 83: 89-105. PMID: 33412218
- Carbenoxolone has the potential to ameliorate acute incision pain in rats. | Dong, S., et al. 2021. Mol Med Rep. 24: PMID: 34013377
- Comparative effect of vitamin D3 and carbenoxolone treatments in metabolic syndrome rats. | Saleh, N., et al. 2022. Can J Physiol Pharmacol. 100: 412-421. PMID: 34855519
- Carbenoxolone Ameliorates Allergic Airway Inflammation through NF-κB/NLRP3 Pathway in Mice. | He, F., et al. 2022. Biol Pharm Bull. 45: 743-750. PMID: 35431287
Inhibitor of:
11β-HSD1L, 11β-HSD2, Bestrophin (BEST), Bestrophin-3, CALHM2, connexin 26, connexin 31, connexin 33, connexin 39, connexin 45, GAPDH, LRRC8A, LRRC8E, OR4D9, Pannexin-2, Pannexin-3, PU.1, SerpinA6, SF-1, T2R8, and Vmn2r107.Activator of:
11β-HSD1L, connexin 31.1, connexin 39, and connexin 50.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carbenoxolone, 1 g | sc-507294 | 1 g | $50.00 |