OR2A42 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine may inhibit the functional activity of OR2A42 by competitively binding to adenosine receptors, which are known to modulate olfactory signaling. This competitive inhibition can alter the perception of odors by affecting the signaling events in olfactory sensory neurons where OR2A42 is expressed. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Copper(II) sulfate can bind to and block sulfhydryl groups on proteins, potentially altering the conformation of OR2A42 and inhibiting its function as an odorant receptor by affecting its ability to interact with odorant molecules. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc acetate is known to interact with sulfhydryl groups on proteins. It may inhibit OR2A42 by modifying the receptor's active sites, which could prevent odorant molecule binding and signal transduction. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $50.00 $128.00 | ||
Lidocaine, as a local anesthetic, can inhibit sodium channels on neurons. By blocking these channels on olfactory sensory neurons, it may indirectly inhibit the signaling cascade that OR2A42 is involved in, leading to reduced receptor activity. | ||||||
Quinine | 130-95-0 | sc-212616 sc-212616A sc-212616B sc-212616C sc-212616D | 1 g 5 g 10 g 25 g 50 g | $77.00 $102.00 $163.00 $347.00 $561.00 | 1 | |
Quinine, which blocks potassium channels, could inhibit the depolarization of olfactory sensory neurons and, as a consequence, indirectly inhibit the activity of OR2A42 by preventing the initiation of olfactory signal transduction. | ||||||
α-Iodoacetamide | 144-48-9 | sc-203320 | 25 g | $250.00 | 1 | |
Iodoacetamide irreversibly modifies cysteine residues in proteins. By alkylating cysteine residues in OR2A42, it could prevent the proper functioning of the receptor by altering its structure or blocking its active site. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $112.00 $371.00 $1060.00 | 1 | |
Silver nitrate can interact with and precipitate proteins. This interaction may inhibit OR2A42 by causing conformational changes or aggregation, thus impacting the receptor's ability to bind to odorant molecules. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $184.00 $245.00 | 13 | |
Ruthenium red is an inhibitor of calcium channels. By inhibiting calcium influx in olfactory sensory neurons, it could indirectly decrease the functional activity of OR2A42, as calcium signaling is essential for olfactory transduction. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin is an agonist for TRPV1 receptors but can also affect other sensory neurons. It may lead to a desensitization of the sensory pathways that include OR2A42, ultimately reducing the receptor's functional response to odorant stimuli. | ||||||