Date published: 2026-1-22

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OPA1 Antibodies

Santa Cruz Biotechnology offers a broad range of OPA1 monoclonal antibodies for research in mitochondrial dynamics and function. OPA1 monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). OPA1, a dynamin-related GTPase, plays a crucial role in the regulation of mitochondrial fusion and is essential for maintaining mitochondrial morphology and function. Dysregulation of OPA1 has been implicated in various neurodegenerative diseases and metabolic disorders, highlighting its importance in cellular health and energy metabolism. Understanding the function of OPA1 is vital for elucidating the mechanisms underlying these diseases and developing potential therapeutic strategies. OPA1 monoclonal antibodies enable researchers to investigate mitochondrial dynamics in both normal and pathological conditions. Studying OPA1's role in mitochondrial fusion provides insights into cellular energy production and maintenance. Research with OPA1 monoclonal antibodies contributes to advancing our understanding of neurodegenerative diseases and potential treatments. Santa Cruz Biotechnology monoclonal antibodies support the scientific community in uncovering new insights into mitochondrial biology and disease mechanisms.

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OPA1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

OPA1 Antibody (D-9)

sc-393296mouse IgG1 κ647-780 (h)WB, IP, IF, ELISAm, r, h
61
(22)

OPA1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OPA1 CRISPR/Cas9 KO Plasmid (h)

sc-401555hGene KnockoutGFP0
(0)

OPA1 HDR Plasmid (h)

sc-401555-HDRhHomology Directed RepairPuromycin0
(0)

OPA1 Double Nickase Plasmid (h)

sc-401555-NIChGene KnockoutPuromycin0
(0)

OPA1 Double Nickase Plasmid (h2)

sc-401555-NIC-2hGene KnockoutPuromycin0
(0)

OPA1 CRISPR/Cas9 KO Plasmid (m)

sc-428749mGene KnockoutGFP0
(1)

OPA1 HDR Plasmid (m)

sc-428749-HDRmHomology Directed RepairPuromycin0
(1)

OPA1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OPA1 CRISPR Activation Plasmid (h)

sc-401555-ACThGene ActivationPuro, Blast, Hygro0
(0)

OPA1 CRISPR Activation Plasmid (m)

sc-428749-ACTmGene ActivationPuro, Blast, Hygro0
(1)

OPA1 CRISPR Activation Plasmid (m2)

sc-428749-ACT-2mGene ActivationPuro, Blast, Hygro0
(1)

OPA1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OPA1 siRNA (h)

sc-106808hGene SilencingN/A
4
(0)

OPA1 shRNA Plasmid (h)

sc-106808-SHhGene SilencingPuromycin
4
(0)

OPA1 shRNA (h) Lentiviral Particles

sc-106808-VhGene SilencingPuromycin
4
(0)

OPA1 siRNA (m)

sc-151306mGene SilencingN/A
2
(0)

OPA1 shRNA Plasmid (m)

sc-151306-SHmGene SilencingPuromycin
2
(0)

OPA1 shRNA (m) Lentiviral Particles

sc-151306-VmGene SilencingPuromycin
2
(0)