Olfr898 Activators
Olfr898 is an olfactory receptor protein responsible for detecting and transducing specific odorant signals, enabling us to perceive and differentiate various scents in our environment. Activation of Olfr898 involves a complex interplay of chemicals and signaling pathways that collectively contribute to its functional role in odor detection. The primary function of Olfr898 is to recognize and respond to specific odorants. When an odorant molecule binds to Olfr898, it undergoes a conformational change that activates the receptor. This activation can occur through direct binding of chemicals like Ethyl Benzoate and Isoamyl Acetate to Olfr898's receptor site, or indirectly through the modulation of intracellular pathways like the cAMP-dependent PKA pathway by chemicals like 8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) and 3-Methyl-2-oxovaleric acid.
Indirect activators, such as Geraniol and Eugenol, influence Olfr898 by up-regulating its expression through specific signaling pathways. These chemicals enhance the synthesis of Olfr898 protein, resulting in an increased number of active receptors on the cell membrane and functional enhancement of odorant sensitivity. In summary, Olfr898 plays a crucial role in our sense of smell, and its activation is orchestrated by a diverse range of chemicals that either directly or indirectly enhance its responsiveness to odorants, allowing us to perceive and distinguish various scents in our environment.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl Acetate directly activates Olfr898 by binding to its receptor site, inducing a conformational change that triggers intracellular signaling cascades through G-proteins, ultimately leading to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl Salicylate directly activates Olfr898 by binding to its receptor site, initiating a conformational change that triggers intracellular signaling cascades through G-proteins. This leads to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $43.00 $66.00 $117.00 | 3 | |
Allyl Isothiocyanate directly activates Olfr898 by binding to its receptor site, inducing a conformational change that triggers intracellular signaling cascades through G-proteins, ultimately leading to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate directly activates Olfr898 by binding to its receptor site, initiating a conformational change that triggers intracellular signaling cascades through G-proteins. This leads to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
Anethole directly activates Olfr898 by binding to its receptor site, initiating a conformational change that triggers intracellular signaling cascades through G-proteins, ultimately leading to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde directly activates Olfr898 by binding to its receptor site, inducing a conformational change that triggers intracellular signaling cascades through G-proteins. This leads to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin directly activates Olfr898 by binding to its receptor site, initiating a conformational change that triggers intracellular signaling cascades through G-proteins. This leads to the functional activation of Olfr898 in olfactory signal transduction. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) indirectly activates Olfr898 by enhancing cAMP-dependent protein kinase (PKA) phosphorylation of olfactory receptors. This amplifies the receptor's sensitivity to odorants and promotes the functional activation of Olfr898 in odor detection. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol indirectly activates Olfr898 by up-regulating its expression through specific signaling pathways. This enhances the synthesis of Olfr898 protein, resulting in an increased number of active receptors on the cell membrane and functional enhancement of odorant sensitivity. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol indirectly activates Olfr898 by up-regulating its expression through specific signaling pathways. This enhances the synthesis of Olfr898 protein, resulting in an increased number of active receptors on the cell membrane and functional enhancement of odorant sensitivity. | ||||||