Olfr830 Activators
Olfr830 is an olfactory receptor gene encoding a protein that is part of the G protein-coupled receptor (GPCR) family. These receptors are integral to the olfactory system, playing a crucial role in the detection and perception of odors. Olfactory receptors like Olfr830 are primarily located in the olfactory epithelium, where they bind to odorant molecules and initiate a signal transduction pathway that leads to the perception of smell. Activation of Olfr830, as with other olfactory receptors, involves the direct binding of specific odorant molecules. This binding is essential for triggering a conformational change in the receptor, which in turn activates a G protein. The activated G protein stimulates adenylate cyclase, leading to an increase in cyclic AMP (cAMP) levels. Elevated cAMP levels activate protein kinase A (PKA), which then phosphorylates various cellular targets, resulting in the opening of ion channels. This leads to an influx of calcium and sodium ions into the cell, generating an electrical signal that is transmitted to the brain, where it is interpreted as a specific odor.
The specificity of Olfr830's activation is determined by the structural compatibility of the odorant molecules with the receptor. The chemicals listed in the table have been selected based on their potential to fit into the active site of Olfr830, thereby directly activating the receptor through a lock-and-key mechanism. This direct interaction is critical for the functional activation of Olfr830 and the initiation of the olfactory signaling cascade. The process is essential for the perception of odors, highlighting the intricate relationship between the chemical structure of odorants and the activation of specific olfactory receptors. The ability of these chemicals to activate Olfr830 underscores the diversity and complexity of the olfactory system and its critical role in the sensory experience of smell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr830 by directly binding to its ligand-binding domain, leading to a conformational change in the protein and initiation of the olfactory signaling pathway. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, with its fruity aroma, activates Olfr830 through direct interaction with the receptor site. This binding induces a structural change in the receptor, initiating the olfactory signaling mechanism. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, a compound with a floral scent, activates Olfr830 by directly binding to the receptor, causing a conformational change that leads to the activation of olfactory signaling pathways. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, known for its rose-like aroma, activates Olfr830 by directly binding to the receptor, leading to a conformational change and the activation of olfactory signaling mechanisms. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a terpene alcohol with a floral scent, activates Olfr830 by interacting directly with the receptor, causing a structural change and initiating the olfactory signaling pathway. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, an ester of salicylic acid, activates Olfr830 by fitting into its binding pocket. This interaction leads to the receptor's conformational change, triggering the olfactory signaling pathway. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene, a bicyclic monoterpene, activates Olfr830 through direct binding. Its molecular structure allows for effective interaction with the receptor, leading to activation and signal transduction in olfactory neurons. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a citrus-scented terpene, activates Olfr830 by directly interacting with its ligand-binding domain, causing a structural change and initiating the olfactory signaling cascade. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, with its fruity scent, activates Olfr830 by binding to the receptor's active site, triggering a conformational change and the initiation of olfactory signal transduction. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin, a phenolic aldehyde, activates Olfr830 through direct interaction. This compound fits into the receptor's binding site, causing a structural change that leads to the activation of the olfactory signaling pathway. | ||||||