Olfr74 Activators
Olfr74 is a specific olfactory receptor, part of the G-protein coupled receptor (GPCR) family. These receptors are pivotal in the olfactory system, enabling the detection of a wide array of odorant molecules. Each olfactory receptor, including Olfr74, is tuned to detect certain chemical compounds, which allows the olfactory system to discriminate among different odors. The activation of Olfr74, like other olfactory receptors, is a complex process that begins with the binding of an odorant molecule to the receptor. This binding event is highly specific, as each receptor has a unique conformation that allows it to interact with particular molecular structures.
Upon binding of an appropriate odorant, such as those listed above, Olfr74 undergoes a conformational change. This change is critical as it triggers the activation of the associated G-protein, which is an essential step in the signal transduction pathway. The activated G-protein then initiates a cascade of intracellular events, typically involving the production of second messengers like cyclic AMP (cAMP). These messengers amplify the signal and lead to a series of cellular responses that ultimately result in the perception of an odor. The specificity of this response is what allows the olfactory system to accurately identify and discriminate between different scents. The chemicals identified as potential activators of Olfr74 are diverse, encompassing various scents from fruity to floral to minty. Each of these chemicals has the capability to bind to and activate Olfr74, highlighting the receptor's role in detecting a broad spectrum of odorant molecules. This diversity in potential activators reflects the intricate nature of olfactory perception, where slight variations in molecular structure can lead to the activation of different receptors, thereby contributing to the rich tapestry of smells that can be detected and recognized by the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, a fruity-smelling ester, is a potential activator of Olfr74. Its small, volatile nature allows it to interact with olfactory receptors. Upon binding to Olfr74, ethyl butyrate can induce a conformational change in the receptor, resulting in the activation of G-protein mediated signaling cascades, integral to the sensory perception of smell. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
D-Limonene, a citrus-scented terpene, can activate Olfr74 through direct interaction. As a common component of citrus fruit odors, limonene binds to and activates olfactory receptors like Olfr74, triggering G-protein signaling pathways that are essential for the perception of citrus aromas. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a naturally occurring terpene alcohol found in many flowers and spice plants, can activate Olfr74. Its interaction with olfactory receptors involves binding to the receptor, inducing a change that activates the G-protein, thus triggering the signaling pathways responsible for olfactory perception. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, a compound with a grassy odor, can activate Olfr74 through direct binding. As an aldehyde, it interacts with olfactory receptors by binding to them, leading to the activation of the G-protein coupled receptor pathway, a key mechanism in the detection of different odors. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, known for its lemon scent, can activate Olfr74 by directly interacting with the receptor. This interaction leads to the activation of G-protein signaling pathways, which are crucial for the transduction of olfactory signals and perception of lemon-like odors. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a monoterpenoid and alcohol, is a potential activator of Olfr74. By binding to the receptor, geraniol triggers a conformational change, leading to the activation of downstream G-protein mediated signaling pathways, thus participating in the olfactory perception process. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, commonly known as wintergreen oil, can activate Olfr74. This ester, with its minty scent, can bind and activate olfactory receptors, leading to G-protein activation and subsequent signaling required for the perception of minty aromas. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
α-Pinene, a major component of pine resin, can activate Olfr74 by binding to it. This interaction induces a conformational change in the receptor, which in turn activates the G-protein, leading to the initiation of signaling pathways essential for the detection of pine-like scents. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
β-Ionone, known for its floral aroma, can activate Olfr74 through direct interaction. By binding to the receptor, β-ionone induces a conformational change, activating G-protein signaling pathways, which are integral to the process of olfactory perception, particularly of floral scents. | ||||||
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, with a sweet and floral aroma, can activate Olfr74. Its interaction with olfactory receptors involves direct binding, which leads to the activation of the G-protein coupled signaling pathway, crucial for the transduction of sweet and floral scents. | ||||||