Molecular structure of Acetophenone, CAS Number: 98-86-2
Acetophenone (CAS 98-86-2)
Alternate Names:
Methyl phenyl ketone
CAS Number:
98-86-2
Purity:
99%
Molecular Weight:
120.15
Molecular Formula:
C8H8O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Acetophenone functions as a precursor in the synthesis of various organic compounds. Its mechanism of action involves participating in Friedel-Crafts acylation reactions, where it acts as an acylating agent to introduce the acyl group into aromatic compounds. This process involves the activation of the carbonyl group in acetophenone by a Lewis acid catalyst, followed by the attack of the aromatic ring to form a new carbon-carbon bond. This mechanism allows for the production of a wide range of substituted aromatic ketones, which are intermediates in the synthesis of agrochemicals and other fine chemicals. Acetophenone can also undergo reduction to form phenylethanol, which is utilized in the fragrance industry. Its ability to undergo these chemical transformations makes acetophenone a versatile building block in organic synthesis.
Acetophenone (CAS 98-86-2) References
- Acetophenone derivatives from Acronychia pedunculata. | Su, CR., et al. 2003. J Nat Prod. 66: 990-3. PMID: 12880321
- Acetophenone as an anti-attractant for the western pine beetle, Dendroctonus Brevicomis LeConte (Coleoptera: Scolytidae). | Erbilgin, N., et al. 2007. J Chem Ecol. 33: 817-23. PMID: 17318432
- Cytotoxic prenylated acetophenone dimers from Acronychia pedunculata. | Kouloura, E., et al. 2012. J Nat Prod. 75: 1270-6. PMID: 22708987
- A new acetophenone glycoside from the flower buds of Syzygium aromaticum (cloves). | Ryu, B., et al. 2016. Fitoterapia. 115: 46-51. PMID: 27702665
- Acetophenone Monomers from Acronychia trifoliolata. | Miyake, K., et al. 2016. J Nat Prod. 79: 2883-2889. PMID: 27797192
- Modification of the response of olfactory receptors to acetophenone by CYP1a2. | Asakawa, M., et al. 2017. Sci Rep. 7: 10167. PMID: 28860658
- RIFM fragrance ingredient safety assessment, acetophenone, CAS Registry Number 98-86-2. | Api, AM., et al. 2018. Food Chem Toxicol. 118 Suppl 1: S162-S169. PMID: 29936279
- Differential effects of acetophenone on shoots' and roots' metabolism of Solanum nigrum L. plants and implications in its phytoremediation. | Moreira, JT., et al. 2018. Plant Physiol Biochem. 130: 391-398. PMID: 30064095
- Acetophenone benzoylhydrazones as antioxidant agents: Synthesis, in vitro evaluation and structure-activity relationship studies. | Emami, S., et al. 2018. Food Chem. 268: 292-299. PMID: 30064761
- Acetophenone derivatives from the roots of Melicope ptelefolia. | Xu, QQ., et al. 2019. Fitoterapia. 132: 40-45. PMID: 30496807
- Two novel coumarins bearing an acetophenone derivative from the leaves of Melicope Quercifolia. | Saputri, RD., et al. 2021. Nat Prod Res. 35: 1256-1261. PMID: 31328970
- Pharmacology of apocynin: a natural acetophenone. | Savla, SR., et al. 2021. Drug Metab Rev. 53: 542-562. PMID: 33689526
- Dibenzofuran, 4-Chromanone, Acetophenone, and Dithiecine Derivatives: Cytotoxic Constituents from Eupatorium fortunei. | Chang, CH., et al. 2021. Int J Mol Sci. 22: PMID: 34299072
- Traveling across Life Sciences with Acetophenone-A Simple Ketone That Has Special Multipurpose Missions. | Zubkov, FI. and Kouznetsov, VV. 2023. Molecules. 28: PMID: 36615564
Inhibitor of:
Olfr1040, Olfr1054, Olfr1082, Olfr299, Olfr304, Olfr308, Olfr311, Olfr365, Olfr366, Olfr403, Olfr414, Olfr434, Olfr450, Olfr734, Olfr8, OR2T2, OR4F15, OTTMUSG00000017864, OTTMUSG00000017866, Vmn1r175, Vmn2r117, and Vmn2r40.Activator of:
Olfr1019, Olfr1023, Olfr1028, Olfr1036, Olfr1040, Olfr1043, Olfr1045, Olfr1049, Olfr1056, Olfr1066, Olfr1097, Olfr1106, Olfr1109, Olfr151, Olfr30, Olfr313, Olfr317, Olfr319, Olfr320, Olfr331, Olfr338, Olfr340, Olfr342, Olfr345, Olfr347, Olfr351, Olfr353, Olfr355, Olfr357, Olfr358, Olfr360, Olfr397, Olfr412, Olfr414, Olfr42, Olfr429, Olfr435, Olfr517, Olfr518, Olfr519, Olfr551, Olfr575, Olfr596, Olfr617, Olfr624, Olfr627, Olfr63, Olfr630, Olfr631, Olfr672, Olfr681, Olfr704, Olfr722, Olfr724, Olfr74, Olfr769, Olfr782, Olfr828, Olfr835, Olfr853, Olfr854, Olfr855, Olfr857, Olfr859, Olfr874, Olfr875, Olfr906, Olfr913, Olfr934, Olfr95, Olfr951, Olfr957, Olfr958, Olfr959, Olfr960, Olfr972, Olfr983, OR11A1, OR11H12, OR1A1, OR2A5, OR2AJ1, OR2G3, OR2T2, OR4A5, OR4C15, OR4K1, OR51A2, OR51H1, OR51L1, OR51T1, OR52I2, OR52N4, OR5A2, OR5B3, OR5D18, OR7C2, OR8D4, OR8U1, OR9G9, Vmn1r120, Vmn1r15, Vmn1r152, Vmn1r191, Vmn1r196, Vmn1r221, Vmn1r34, Vmn1r61, and Vmn1r88.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acetophenone, 5 g | sc-239189 | 5 g | $20.00 |