Olfr544 Activators
Olfr544 activators are molecules that can modulate G protein signaling, adenylate cyclase activity, and intracellular calcium and cAMP levels. These compounds might indirectly influence the functional activity of Olfr544 by affecting the common signaling pathways that GPCRs are involved in.
Forskolin, IBMX, Cholera toxin, Pertussis toxin, SQ 22536, and NF449 are all compounds that could potentially modulate adenylate cyclase activity or G protein signaling. Forskolin stimulates adenylate cyclase, increasing cAMP levels, while IBMX inhibits phosphodiesterase, preventing cAMP degradation. Cholera toxin could potentially prolong the activation of the Gs protein, and Pertussis toxin could decrease the inhibition of adenylate cyclase. SQ 22536 is an adenylate cyclase inhibitor, and NF449 is a potent Gs protein inhibitor. Picrotoxin, a GABAA receptor antagonist, could potentially increase neuronal excitability and indirectly influence olfactory signal transduction. Capsaicin could potentially increase intracellular calcium levels. Gallein, a Gβγ signaling inhibitor, GDP-β-S, a non-hydrolyzable GDP analogue, and YM-254890, a selective Gq protein inhibitor, could also potentially modulate G protein signaling. Finally, U73122 is a phospholipase C inhibitor that could potentially influence the downstream signaling of Olfr544.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
May stimulate adenylate cyclase, increasing cAMP levels and potentially activating the Gs protein associated with Olfr544. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
A GABAA receptor antagonist that could potentially increase neuronal excitability and indirectly influence olfactory signal transduction. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Could potentially increase intracellular calcium levels, influencing downstream signaling of Olfr544. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
As a nonselective phosphodiesterase inhibitor, it could potentially increase cAMP levels enhancing Gs protein signal transduction. | ||||||
Pertussis Toxin (islet-activating protein) | 70323-44-3 | sc-200837 | 50 µg | $451.00 | 3 | |
It could potentially ADP-ribosylate Gi/o proteins, potentially leading to decreased inhibition of adenylate cyclase. | ||||||
Gallein | 2103-64-2 | sc-202631 | 50 mg | $85.00 | 20 | |
A Gβγ signaling inhibitor that could potentially modulate G protein signaling associated with Olfr544. | ||||||
SQ 22536 | 17318-31-9 | sc-201572 sc-201572A | 5 mg 25 mg | $95.00 $363.00 | 13 | |
An adenylate cyclase inhibitor that could potentially modulate adenylate cyclase activity influencing the cAMP pathway. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
A potent Gs protein inhibitor that could potentially modulate Gs protein signal transduction. | ||||||
YM 254890 | 568580-02-9 | sc-507356 | 1 mg | $510.00 | ||
A selective Gq protein inhibitor that could potentially modulate G protein signaling associated with Olfr544. | ||||||