Olfr49 Activators
Chemical activators of Olfr49, as proposed in this list, are based on the typical activation mechanisms of olfactory receptors. These chemicals, such as Ethyl propionate, Butyl acetate, and Isoamyl alcohol, are hypothesized to interact directly with Olfr49, a G-protein-coupled receptor (GPCR). Upon binding to Olfr49, these compounds are likely to induce a conformational change in the receptor, initiating a cascade of intracellular events characteristic of GPCR activation. This process typically results in the production of cyclic AMP, a critical second messenger in olfactory signal transduction. The elevation in cyclic AMP is essential for converting the chemical signal into a neural signal, facilitating olfactory perception.
Other compounds like Amyl butyrate, Hexyl acetate, and Benzyl alcohol are also hypothesized to function similarly, binding to Olfr49 and activating the GPCR pathway. Each of these chemicals has a unique molecular structure that allows specific interaction with Olfr49, triggering the receptor's activation. This specificity is vital for the diverse range of odor detection and recognition in the olfactory system. The proposed activation of Olfr49 by these chemicals underscores the intricate molecular dynamics involved in olfactory perception and the sophisticated nature of GPCR-mediated signal transduction in the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl propionate | 105-37-3 | sc-214997 sc-214997A | 25 ml 500 ml | $15.00 $39.00 | ||
Ethyl propionate, with a fruity and rum-like scent, may activate Olfr49 by direct binding, potentially inducing a conformational change in the receptor and initiating the GPCR signaling pathway, leading to increased cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
Butyl acetate | 123-86-4 | sc-214637 sc-214637A | 1 ml 5 ml | $20.00 $77.00 | ||
Butyl acetate, known for its sweet fruity aroma, could activate Olfr49 through direct interaction with its ligand-binding domain, triggering the GPCR pathway and resulting in elevated cyclic AMP, essential for olfactory signal processing. | ||||||
3-Methyl-1-butanol | 123-51-3 | sc-231818 sc-231818A | 500 ml 1 L | $70.00 $93.00 | ||
Isoamyl alcohol, found in bananas and pears, may bind directly to Olfr49, inducing a structural change in the receptor. This activates the GPCR mechanism, leading to increased cyclic AMP and olfactory signal transduction. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, possessing a green fruity scent, could activate Olfr49 by direct binding, leading to GPCR pathway activation and subsequent increase in cyclic AMP, crucial for olfactory signal transmission. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $31.00 $102.00 $408.00 | ||
Benzyl alcohol, with a mild floral aroma, may activate Olfr49 through direct binding to the receptor, triggering the GPCR signaling pathway and resulting in increased cyclic AMP, essential for olfactory signal transduction. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, known for its pineapple-like scent, might activate Olfr49 through direct receptor binding, triggering the GPCR mechanism and increasing cyclic AMP levels, crucial for olfactory signal transduction. | ||||||
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl acetate, with its fruity aroma, could activate Olfr49 by direct interaction, initiating the GPCR pathway and leading to an elevation in cyclic AMP, important for olfactory signal processing. | ||||||
Methyl butyrate | 623-42-7 | sc-215339 sc-215339A | 1 kg 5 kg | $95.00 $210.00 | ||
Methyl butyrate, with an apple-like aroma, potentially activates Olfr49 by direct binding, leading to GPCR pathway activation and a subsequent rise in cyclic AMP, essential for olfactory signaling. | ||||||
Butyl butyrate | 109-21-7 | sc-239439 | 250 ml | $210.00 | ||
Butyl butyrate, common in pineapples, may activate Olfr49 through direct interaction with the receptor, initiating the GPCR signaling pathway and resulting in increased cyclic AMP, important for olfactory signal transduction. | ||||||
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $65.00 | ||
Pentyl acetate, with a pear-like scent, might activate Olfr49 through direct receptor interaction, leading to the activation of the GPCR pathway and a rise in cyclic AMP, essential for olfactory signal processing. | ||||||