Date published: 2025-10-15

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Methyl butyrate (CAS 623-42-7)

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CAS Number:
623-42-7
Molecular Weight:
102.13
Molecular Formula:
C5H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl butyrate, cataloged under CAS number 623-42-7, is a methyl ester of butyric acid, characterized by its fruity aroma reminiscent of apples or pineapples, making it popular in flavor and fragrance industries. Beyond its commercial applications, methyl butyrate is a valuable compound in scientific research, particularly in the study of organic synthesis and esterification processes. This ester serves as a model compound for investigating the kinetics and mechanisms of ester formation, a fundamental reaction in organic chemistry where an acid reacts with an alcohol, yielding an ester and water. Methyl butyrate′s relatively simple structure allows researchers to study esterification under various conditions without the complications presented by more complex molecules. In chemical synthesis, it provides insights into reaction conditions that optimize yield and selectivity for ester production. Furthermore, methyl butyrate is utilized in analytical chemistry as a standard for calibrating instruments designed to detect and measure volatile organic compounds. Its distinct and strong odor profile makes it ideal for studies in olfactory response and the development of synthetic aroma compounds. Additionally, its role in food chemistry research includes exploring the impact of esters on flavor profiles and stability, contributing to the development of new food products and enhancement of existing ones.


Methyl butyrate (CAS 623-42-7) References

  1. Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver.  |  Yang, J., et al. 2022. Cell Immunol. 378: 104575. PMID: 35779312
  2. Comparative analysis of aroma components and quality of Geotrichum candidum after space mutation breeding.  |  Chen, J., et al. 2022. Front Microbiol. 13: 908329. PMID: 35935228
  3. RIFM fragrance ingredient safety assessment, methyl butyrate, CAS registry number 623-42-7.  |  Api, AM., et al. 2022. Food Chem Toxicol. 169 Suppl 1: 113494. PMID: 36273717
  4. Identification of Volatile Markers during Early Zygosaccharomyces rouxii Contamination in Mature and Immature Jujube Honey.  |  Wang, Y., et al. 2023. Foods. 12: PMID: 37509822
  5. Fecal Microbiota and Associated Volatile Organic Compounds Distinguishing No-Adenoma from High-Risk Colon Adenoma Adults.  |  Katsaounou, K., et al. 2023. Metabolites. 13: PMID: 37512526
  6. Analysis of Volatile Esters and Alkanoic Acids by an Atmospheric Pressure Corona Discharge Ionization Collision-Induced Dissociation Mass Spectrometry in Positive-Ion Mode: Ionization, Fragmentation Patterns, and Discrimination between Isomeric Compounds.  |  Nishikido, Y. and Sekimoto, K. 2023. Mass Spectrom (Tokyo). 12: A0127. PMID: 37538446
  7. Autotrophic Production of the Sesquiterpene α-Humulene with Cupriavidus necator in a Controlled Bioreactor.  |  Sydow, A., et al. 2023. Bioengineering (Basel). 10: PMID: 37892924
  8. Flavor Quality Analysis of Ten Actinidia arguta Fruits Based on High-Performance Liquid Chromatography and Headspace Gas Chromatography-Ion Mobility Spectrometry.  |  Wen, J., et al. 2023. Molecules. 28: PMID: 38005281
  9. Advancing material property prediction: using physics-informed machine learning models for viscosity.  |  Chew, AK., et al. 2024. J Cheminform. 16: 31. PMID: 38486289
  10. Influence of germination and roasting on the characteristic volatile organic compounds of quinoa using sensory evaluation, E-nose, HS-GC-IMS, and HS-SPME-GC-MS.  |  Peng, S., et al. 2024. Food Chem X. 22: 101441. PMID: 38756471

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl butyrate, 1 kg

sc-215339
1 kg
$95.00

Methyl butyrate, 5 kg

sc-215339A
5 kg
$210.00