Olfr378 Activators
Chemical activators of Or1e19, a G-protein-coupled olfactory receptor, are characterized by their ability to specifically interact with and activate this receptor. Compounds such as Ethyl butyrate, Isoamyl acetate, and Benzyl acetate effectively bind to the GPCR structure of Or1e19. This interaction triggers conformational changes essential for the receptor's activation and the effective transduction of olfactory signals via G protein-coupled pathways. The specificity of these interactions plays a crucial role in enhancing Or1e19's ability to recognize and respond to different odorants.
Additionally, chemicals like Hexyl acetate, Octanal, Nonanal, and Decanal demonstrate a similar mechanism of activation. They interact with various domains of Or1e19, inducing structural modifications that lead to the receptor's functional activation. This activation is pivotal for initiating G protein-coupled odorant signal transduction processes. Other activators, including Citronellol, Geraniol, Linalool, Methyl salicylate, and Eugenol, engage with Or1e19's structure, resulting in conformational changes that potentiate the receptor's olfactory signal transduction capabilities. Each of these chemicals contributes to the functional activation of Or1e19 by influencing its structural and conformational dynamics, which are critical for effective olfactory signal transduction and perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Or1e19 by binding to its GPCR structure, inducing a conformational change that triggers G protein-mediated signal transduction specific to olfactory perception. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate interacts with Or1e19, facilitating its activation through a mechanism involving binding to the olfactory receptor domain, enhancing odorant signal recognition and transduction. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $29.00 | 1 | |
Benzyl acetate activates Or1e19 by engaging its ligand-binding site, causing a structural alteration that leads to the initiation of G protein-coupled olfactory signaling pathways. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate binds to the active site of Or1e19, inducing a conformational change that triggers the receptor's activation and subsequent olfactory signal transduction via G protein pathways. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $25.00 $33.00 | ||
Octanal activates Or1e19 by interacting with its extracellular domain, leading to a conformational change and the activation of G protein-coupled intracellular signaling related to olfaction. | ||||||
Nonanal | 124-19-6 | sc-257926 | 1 g | $66.00 | ||
Nonanal engages Or1e19, activating it by altering its conformation and thereby enhancing the receptor's ability to initiate olfactory signal transduction processes. | ||||||
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal activates Or1e19 by binding to its GPCR domain, causing a structural shift that enables the initiation of G protein-coupled odorant signal transduction. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $31.00 $153.00 | ||
(±)-β-Citronellol interacts with Or1e19, causing a conformational alteration that leads to the activation of G protein-coupled signaling mechanisms specific to olfactory perception. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol binds to Or1e19's ligand-binding region, inducing a conformational change that facilitates G protein-coupled odorant signal transduction. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool activates Or1e19 by engaging with its extracellular domain, leading to a structural alteration that triggers G protein-mediated olfactory signal transduction. | ||||||