Olfr346 Activators
Chemical activators of Olfr346 include a variety of compounds that bind to the ligand-binding domain of this G protein-coupled receptor (GPCR), triggering a signaling cascade responsible for olfactory perception. Citral, a compound known for its lemon scent, engages with Olfr346 through direct binding to the receptor, which induces a conformational change necessary for the activation of the signaling pathway. Similarly, eucalyptol, recognized for its eucalyptus-like aroma, interacts with Olfr346, causing activation through conformational alterations that lead to signal transduction. Geraniol, with its rose-like fragrance, serves as a direct agonist, initiating a conformational shift in Olfr346 that activates the olfactory signal transduction mechanism. Phenylethyl alcohol, another activator, binds to Olfr346, promoting a structural reorganization that triggers downstream signaling.
Further, benzaldehyde and isoamyl acetate bind to specific pockets within Olfr346, catalyzing changes in the tertiary structure that activate the G protein-coupled signaling pathway. Ethyl vanillin and methyl salicylate engage with Olfr346, fitting into its ligand-binding domain to cause conformational changes that lead to activation of the olfactory signaling cascade. Linalool, recognized for its floral scent, activates Olfr346 by eliciting a conformational rearrangement that triggers the associated signaling mechanism. Limonene, with its citrus scent, and anethole, known for its licorice aroma, activate Olfr346 by promoting a conformational shift and a structural change, respectively, that leads to the activation of the olfactory signaling pathway. Lastly, alpha-pinene, with its pine-like aroma, binds to Olfr346's active site, inducing a structural change that results in the activation of GPCR signaling pathways integral to olfactory function. Each of these chemicals binds directly to Olfr346, effecting a structural alteration that facilitates the transition from an inactive to an active receptor state, thereby initiating the olfactory signal transduction process.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates Olfr346 by binding directly to its ligand-binding domain, which induces a conformational change in the protein that triggers the associated G protein-coupled receptor (GPCR) signaling cascade. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
Eucalyptol interacts with Olfr346, causing an activation of the protein through a conformational change that leads to signal transduction via GPCR pathways. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol serves as a direct agonist for Olfr346, binding to the receptor's active site and initiating a conformational shift that activates the olfactory signal transduction mechanism. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
Phenylethyl alcohol activates Olfr346 by docking to its ligand-binding region, promoting a structural reorganization that triggers the downstream GPCR signaling. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate directly activates Olfr346 by binding to its ligand-binding site, which induces a conformational alteration necessary for the activation of its associated GPCR signaling pathways. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl vanillin engages with Olfr346 by fitting into its ligand-binding domain, causing a change in protein conformation that leads to the activation of the G protein-coupled olfactory signaling cascade. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr346 by binding to the receptor and inducing a conformational change that activates the olfactory G protein-coupled receptor pathways. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool activates Olfr346 through direct binding to the receptor's ligand-binding site, eliciting a conformational rearrangement that triggers the activation of the GPCR signaling mechanism. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates Olfr346 by direct interaction with the receptor's ligand-binding domain, promoting a conformational shift that leads to the activation of the olfactory G protein-coupled signaling pathway. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole activates Olfr346 by directly binding to the receptor, which causes a conformational change that activates the G protein-coupled signaling cascade associated with olfactory perception. | ||||||