Odf3 Inhibitors
Odf3 inhibitors encompass a range of compounds that can disrupt or alter the cytoskeletal architecture and dynamics, thereby indirectly inhibiting the function of Odf3. For instance, compounds like Blebbistatin, Y-27632, ML-7, Latrunculin A, and Cytochalasin D function by disrupting the actin cytoskeleton or the related signaling pathways, such as those regulated by myosin II, Rho-associated protein kinase, and myosin light chain kinase. The inhibition of these enzymes or the prevention of actin polymerization leads to changes in the cytoskeletal organization and dynamics, which is critical for the proper function of Odf3. By altering the cytoskeleton, these compounds indirectly affect the ability of Odf3 to maintain its role in structural organization, particularly within microtubule networks.
Similarly, agents like Paclitaxel, Colchicine, Nocodazole, CK-636, SMIFH2, Vinblastine, and Taxol target microtubule dynamics by either stabilizing microtubules to an extent that prevents their normal function or by inhibiting their polymerization. The functionality of OOdf3 inhibitors encompass a range of compounds that can disrupt or alter the cytoskeletal architecture and dynamics, thereby indirectly inhibiting the function of Odf3. For instance, compounds like Blebbistatin, Y-27632, ML-7, Latrunculin A, and Cytochalasin D function by disrupting the actin cytoskeleton or the related signaling pathways, such as those regulated by myosin II, Rho-associated protein kinase, and myosin light chain kinase. The inhibition of these enzymes or the prevention of actin polymerization leads to changes in the cytoskeletal organization and dynamics, which is critical for the proper function of Odf3. By altering the cytoskeleton, these compounds indirectly affect the ability of Odf3 to maintain its role in structural organization, particularly within microtubule networks.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Myosin II inhibitor that impedes cytoskeletal dynamics. Since Odf3 is associated with the cytoskeleton, the disruption of myosin II activity can lead to altered cytoskeletal organization, potentially disrupting the structural integrity of the microtubule network where Odf3 operates. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Microtubule stabilizer that prevents their disassembly. Odf3 is involved in microtubule organization, and hyperstabilization can paradoxically inhibit proper microtubule function, possibly affecting Odf3's associated processes and leading to its inhibition. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Binds to tubulin, inhibiting polymerization into microtubules. As Odf3 is involved in the structural organization of microtubules, colchicine's action can indirectly inhibit Odf3 by disrupting the microtubule architecture it depends on. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubule polymerization. Odf3 function is closely tied to microtubule dynamics; nocodazole's interference with these dynamics can indirectly inhibit Odf3 by destabilizing the microtubule network. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibitor of ROCK (Rho-associated protein kinase), which is involved in cytoskeletal organization. By inhibiting ROCK, Y-27632 can disrupt cytoskeletal structure and signaling, potentially leading to the functional inhibition of Odf3 which is associated with the cytoskeleton. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
Inhibits formin-mediated actin assembly. Odf3 may be indirectly inhibited by the altered actin dynamics resulting from formin inhibition, as this can impact the structural integrity of actin filaments within the cytoskeleton. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
Inhibitor of myosin light chain kinase (MLCK), involved in cytoskeletal dynamics. By inhibiting MLCK, ML-7 can alter cytoskeletal organization and dynamics, potentially leading to the indirect inhibition of Odf3. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Binds to actin monomers and prevents their polymerization. Such disruption of actin filaments can indirectly inhibit Odf3, as it may rely on the proper formation of the actin cytoskeleton to maintain its function. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Inhibits actin polymerization and induces filament disassembly. This can lead to cytoskeletal disorganization, indirectly inhibiting Odf3 function by altering the cytoskeletal environment it operates within. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Binds to tubulin and inhibits its assembly into microtubules. This disruption of microtubule dynamics can indirectly inhibit Odf3 by compromising the microtubular structure it is associated with. | ||||||