Oatp2 Activators
The chemical class known as OATP2 activator encompasses a group of organic compounds that have been identified for their ability to modulate the function of the Organic Anion Transporting Polypeptide 2 (OATP2) transporter protein. OATP2 is a membrane-bound protein primarily located in various tissues, including the liver and intestine, where it plays a crucial role in the transportation of a diverse range of organic anions. The OATP2 activators are characterized by their capability to enhance the uptake of these organic anions into cells by interacting with the OATP2 transporter. This interaction can lead to an increased rate of cellular uptake and subsequent intracellular accumulation of specific molecules.
The structural diversity within the OATP2 activator class allows for a variety of interactions with the transporter, potentially influencing its conformational changes and facilitating the translocation of substrates across cell membranes. OATP2 activators are studied for their effects on cellular transport processes and their impact on the regulation of substrate distribution within various tissues. Continued research into this chemical class sheds light on the molecular mechanisms underlying OATP2 activation and contributes to a deeper understanding of cellular transport dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
A natural estrogen hormone that has been shown to activate OATP2-mediated transport. | ||||||
L-Thyroxine, free acid | 51-48-9 | sc-207813 sc-207813A | 100 mg 500 mg | $35.00 $74.00 | 2 | |
A thyroid hormone that has been reported to interact with and activate OATP2. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $143.00 $694.00 | ||
A agent in research used to treat heart conditions, which has been studied as a potential activator of OATP2. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $257.00 $505.00 | 9 | |
A statin agent in research used to lower cholesterol levels, which has been investigated for its interaction with OATP2. | ||||||
Pravastatin, Sodium Salt | 81131-70-6 | sc-203218 sc-203218A sc-203218B | 25 mg 100 mg 1 g | $69.00 $162.00 $787.00 | 2 | |
Another statin agent in research that has been studied for its potential effects on OATP2 activation. | ||||||
Efavirenz | 154598-52-4 | sc-207612 | 10 mg | $171.00 | 3 | |
An antiretroviral agent in research used to treat HIV, which has been suggested to activate OATP2. | ||||||
Ritonavir | 155213-67-5 | sc-208310 | 10 mg | $124.00 | 7 | |
Another antiretroviral agent in research that has been investigated for its potential interaction with OATP2. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
An antibiotic often used to treat tuberculosis, which has been shown to affect OATP2 activity. | ||||||
Fexofenadine | 83799-24-0 | sc-218475 | 100 mg | $298.00 | 1 | |
An antihistamine agent in research that has been studied for its potential interaction with OATP2. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $66.00 $267.00 | 2 | |
A agent in research used to lower triglyceride levels, which has been investigated for its effects on OATP2. | ||||||