Date published: 2025-10-3

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Nucleic Acids, Nucleotides and Nucleosides

Santa Cruz Biotechnology now offers a broad range of nucleic acids, nucleotides, and nucleosides for use in various applications. Nucleic acids, including DNA and RNA, are the fundamental molecules of life, encoding the genetic information necessary for the development, functioning, and reproduction of all living organisms. Nucleotides, the building blocks of nucleic acids, and nucleosides, which consist of a nitrogenous base attached to a sugar molecule, play critical roles in numerous biological processes. In scientific research, these compounds are essential for studying genetic expression, regulation, and mutation. They are utilized in techniques such as PCR, sequencing, and gene editing, enabling researchers to explore the complexities of genomes and develop innovative biotechnological applications. Nucleic acids are also pivotal in the study of transcription, translation, and replication, providing insights into cellular mechanisms and the flow of genetic information. In the field of molecular biology, nucleotides and nucleosides are used to investigate enzyme activities, signal transduction pathways, and metabolic processes. Environmental scientists study nucleic acids to monitor biodiversity, track microbial communities, and assess environmental changes. Additionally, in materials science, nucleic acids are harnessed for the development of biosensors, nanomaterials, and bioinformatics tools. The broad applicability and vital roles of nucleic acids, nucleotides, and nucleosides in advancing scientific knowledge and technology make them indispensable tools in research across multiple disciplines. View detailed information on our available nucleic acids, nucleotides, and nucleosides by clicking on the product name.

Items 41 to 50 of 157 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

8-Bromoadenosine 3′,5′-cyclic monophosphate

23583-48-4sc-217493B
sc-217493
sc-217493A
sc-217493C
sc-217493D
25 mg
50 mg
100 mg
250 mg
500 mg
$106.00
$166.00
$289.00
$550.00
$819.00
2
(1)

8-Bromoadenosine 3',5'-cyclic monophosphate is a halogenated derivative of cyclic AMP, characterized by the presence of a bromine atom at the 8-position. This modification can significantly influence its interaction with protein kinases and phosphodiesterases, potentially altering signal transduction pathways. The bromine atom may enhance hydrophobic interactions, affecting the compound's stability and reactivity in biochemical assays, while also modulating its role in cellular signaling cascades.

5′-Deoxy-5-fluorocytidine

66335-38-4sc-221055
10 mg
$100.00
(1)

5'-Deoxy-5-fluorocytidine is a modified nucleoside featuring a fluorine atom at the 5-position, which alters its hydrogen bonding capabilities and steric properties. This substitution can impact its incorporation into nucleic acids, influencing base pairing and stability. The presence of fluorine may enhance resistance to enzymatic degradation, affecting reaction kinetics and the overall dynamics of nucleic acid synthesis. Its unique interactions can lead to distinct conformational changes in nucleic acid structures.

Emtricitabine

143491-57-0sc-207617
10 mg
$149.00
1
(1)

Emtricitabine is a synthetic nucleoside analog characterized by its unique structural modifications that enhance its interaction with nucleic acids. The presence of a thiol group influences hydrogen bonding and base pairing, potentially altering the stability of nucleic acid duplexes. Its distinct molecular conformation can affect the kinetics of polymerase enzymes, leading to variations in replication fidelity. Additionally, the compound's hydrophilic nature may impact solubility and cellular uptake, influencing its behavior in nucleic acid environments.

4-Thiouridine

13957-31-8sc-204628
sc-204628A
5 mg
25 mg
$66.00
$150.00
3
(2)

4-Thiouridine is a modified nucleoside that features a sulfur atom in place of the oxygen at the 4-position of uridine. This substitution enhances its ability to participate in unique base pairing interactions, potentially stabilizing RNA structures. The presence of sulfur can also influence the reactivity of the nucleoside in various biochemical pathways, affecting the kinetics of RNA synthesis and degradation. Its distinct electronic properties may alter the overall charge distribution, impacting molecular interactions within nucleic acid frameworks.

5-Ethynyl-2′-deoxyuridine

61135-33-9sc-284628
sc-284628A
sc-284628B
250 mg
1 g
10 g
$216.00
$571.00
$3570.00
57
(3)

5-Ethynyl-2'-deoxyuridine is a synthetic nucleoside characterized by an ethynyl group at the 5-position, which introduces unique steric and electronic properties. This modification can enhance its incorporation into DNA, influencing replication and repair mechanisms. The presence of the ethynyl moiety may also alter hydrogen bonding patterns, potentially affecting the stability of DNA duplexes. Its distinct structure can modulate interactions with polymerases, impacting reaction kinetics and fidelity during nucleic acid synthesis.

Ganglioside GD3 disodium salt

62010-37-1sc-202623
sc-202623A
sc-202623B
sc-202623C
500 µg
1 mg
10 mg
50 mg
$270.00
$390.00
$2900.00
$13500.00
(1)

Ganglioside GD3 disodium salt is a complex glycosphingolipid that plays a pivotal role in cellular signaling and membrane dynamics. Its unique structure, featuring sialic acid residues, facilitates specific interactions with receptors, influencing cell adhesion and communication. The presence of multiple hydroxyl groups enhances its solubility and reactivity, allowing it to participate in lipid bilayer formation and modulate membrane fluidity. These properties can significantly affect cellular pathways and molecular interactions within the lipid environment.

8-Bromo-cADP-Ribose (8-Br-cADPR)

151898-26-9sc-201514
sc-201514B
100 µg
1 mg
$130.00
$550.00
12
(1)

8-Bromo-cADP-Ribose (8-Br-cADPR) is a potent analog of cyclic ADP-ribose, known for its role in calcium signaling and cellular processes. Its brominated structure enhances its reactivity, allowing for specific interactions with target proteins and enzymes involved in signaling pathways. This compound can modulate the activity of ADP-ribosyltransferases, influencing the dynamics of post-translational modifications. Additionally, its unique conformation can affect binding affinities, altering cellular responses to stimuli.

Thymidine

50-89-5sc-296542
sc-296542A
sc-296542C
sc-296542D
sc-296542E
sc-296542B
1 g
5 g
100 g
250 g
1 kg
25 g
$48.00
$72.00
$265.00
$449.00
$1724.00
$112.00
16
(1)

Thymidine is a nucleoside composed of a thymine base linked to a deoxyribose sugar, playing a crucial role in DNA synthesis. Its unique structure allows for specific hydrogen bonding interactions with complementary bases, facilitating accurate base pairing during replication. Thymidine's phosphorylation to thymidine monophosphate is a key step in nucleotide metabolism, influencing the balance of nucleotides available for DNA polymerization. Its presence is essential for maintaining genomic stability and integrity.

7,8-Dihydro-L-biopterin

6779-87-9sc-202895
sc-202895A
10 mg
50 mg
$220.00
$414.00
1
(1)

7,8-Dihydro-L-biopterin is a pivotal cofactor in various enzymatic reactions, particularly in the biosynthesis of neurotransmitters. Its unique dihydro form allows for specific redox interactions, enhancing electron transfer processes. This compound participates in critical metabolic pathways, influencing the kinetics of enzymatic reactions. Its structural features enable it to stabilize transition states, thereby modulating reaction rates and contributing to cellular homeostasis.

Polyadenylic acid potassium salt

26763-19-9sc-215725
sc-215725A
sc-215725B
sc-215725D
25 mg
100 mg
250 mg
1 g
$124.00
$343.00
$669.00
$1573.00
(0)

Polyadenylic acid potassium salt is a polymeric nucleotide that plays a crucial role in cellular processes, particularly in RNA synthesis and regulation. Its unique polyadenylation structure facilitates interactions with RNA-binding proteins, influencing mRNA stability and translation efficiency. The compound exhibits distinct binding affinities, which can modulate gene expression. Additionally, its high molecular weight contributes to its physical properties, affecting solubility and viscosity in biological systems.